FARP2 Antikörper (AA 601-700) (AbBy Fluor® 594)
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- Target Alle FARP2 Antikörper anzeigen
- FARP2 (FERM, RhoGEF and Pleckstrin Domain Protein 2 (FARP2))
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Bindungsspezifität
- AA 601-700
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser FARP2 Antikörper ist konjugiert mit AbBy Fluor® 594
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Applikation
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Homologie
- Human,Mouse,Rat,Horse,Chicken
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human FARP2
- Isotyp
- IgG
- Top Product
- Discover our top product FARP2 Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- FARP2 (FERM, RhoGEF and Pleckstrin Domain Protein 2 (FARP2))
- Andere Bezeichnung
- FARP2 (FARP2 Produkte)
- Synonyme
- FARP2 antikoerper, wu:fc23d05 antikoerper, wu:fp25d09 antikoerper, MGC131000 antikoerper, FIR antikoerper, FRG antikoerper, PLEKHC3 antikoerper, AI465173 antikoerper, BC009153 antikoerper, D030026M03Rik antikoerper, Fir antikoerper, mKIAA0793 antikoerper, FERM, ARH/RhoGEF and pleckstrin domain protein 2 antikoerper, FERM, RhoGEF and pleckstrin domain protein 2 antikoerper, FERM, ARH/RhoGEF and pleckstrin domain protein 2 L homeolog antikoerper, FARP2 antikoerper, farp2 antikoerper, farp2.L antikoerper, Farp2 antikoerper
- Hintergrund
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Synonyms: FARP 2, FERM, FGD1 related Cdc42 GEF, FIR, FRG, KIAA0793, PLEKHC3, RhoGEF and pleckstrin domain protein 2, FARP2_HUMAN.
Background: FARP2 is a 1,545 amino acid protein that contains one FERM domain, one DH domain and two PH domains. It exists as two alternatively spliced isoforms that are abundantly expressed in brain, lung, and testis as well as in embryonic hippocampal and cortical neurons. FARP2 functions as a Rho-guanine nucleotide exchange factor that activates RAC1 and is thought to regulate neurite remodeling of embryonic neurons. Sema3A binding to neuropilin-1 induces the dissociation of FARP2 from plexin-A1, thereby activating FARP2's Rac GEF activity which is critical for repulsion of outgrowing axons and suppression of neuronal adhesion. Downregulation of the FARP2 gene has been implicated in autism.
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