PRKCSH Antikörper (AA 101-200) (AbBy Fluor® 594)
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- Target Alle PRKCSH Antikörper anzeigen
- PRKCSH (Protein Kinase C Substrate 80K-H (PRKCSH))
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Bindungsspezifität
- AA 101-200
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PRKCSH Antikörper ist konjugiert mit AbBy Fluor® 594
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Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Homologie
- Human,Mouse,Rat,Cow,Pig,Horse
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Glucosidase 2 subunit beta
- Isotyp
- IgG
- Top Product
- Discover our top product PRKCSH Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- PRKCSH (Protein Kinase C Substrate 80K-H (PRKCSH))
- Andere Bezeichnung
- Glucosidase 2 subunit beta (PRKCSH Produkte)
- Synonyme
- AGE-R2 antikoerper, G19P1 antikoerper, PCLD antikoerper, PKCSH antikoerper, PLD1 antikoerper, 80K-H antikoerper, VASAP-60 antikoerper, zgc:55653 antikoerper, prkcsh antikoerper, MGC75615 antikoerper, MGC82696 antikoerper, PRKCSH antikoerper, protein kinase C substrate 80K-H antikoerper, protein kinase C substrate 80K-H L homeolog antikoerper, phospholipase D1 antikoerper, PRKCSH antikoerper, Prkcsh antikoerper, prkcsh antikoerper, prkcsh.L antikoerper, Bm1_42055 antikoerper, LOC100304710 antikoerper, LOC100526729 antikoerper, PLD1 antikoerper
- Hintergrund
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Synonyms: 80K-H protein, AGE-binding receptor 2, AGE-R2, G19P1, GLU2B_HUMAN, Glucosidase 2 subunit beta, Glucosidase II beta subunit, Glucosidase II subunit beta, Hepatocystin, PCLD, PKCSH, PLD1, PRKCSH, Protein kinase C substrate 60.1 kDa protein heavy chain, Protein kinase C substrate 80 Kda protein, Protein kinase C substrate 80K-H, Protein kinase C substrate, 80 Kda protein.
Background: Trimming of glucoses from N-linked core glycans on newly synthesized glycoproteins occurs sequentially through the action of Glucosidases I and II in the endoplasmic reticulum (ER). Glucosidase II is an ER-localized enzyme that contains a and b subunits (Glucosidase IIa and Glucosidase IIb) which form a defined heterodimeric complex. Glucosidase IIa is the catalyitc core of the enzyme and can function independently of the b subunit. The sequence of Glucosidase IIb encodes protein rich in glutamic and aspartic acid with a putative ER retention signal (HDEL) at the C-terminus. The phosphorylated form of Glucosidase IIb is localized in the plasma membrane and is highly expressed in FGF-stimulated fibroblasts and epidermal carcinoma cells. Glucosidase IIb was first purified from a human carcinoma cell line as a potential substrate for protein kinase C. Through the HDEL signal at the C-terminus, Glucosidase IIb retains the complete complex in the ER.
- Gen-ID
- 5589
- Pathways
- Cellular Glucan Metabolic Process, Methionine Biosynthetic Process
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