HCV NS5a Antikörper (AbBy Fluor® 594)

Produktnummer ABIN2814260

Produktdetails anti-HCV NS5a Antikörper (AbBy Fluor® 594)

Target: HCV NS5a (Hepatitis C Virus NS5a (HCV NS5a))

Reaktivität: Virus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HCV NS5a Antikörper ist konjugiert mit AbBy Fluor® 594

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Virus

Kreuzreaktivität (Details): HCV

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from Hepatitis C Virus NS5a

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu HCV NS5a

Target: HCV NS5a (Hepatitis C Virus NS5a (HCV NS5a))

Andere Bezeichnung: Hepatitis C Virus NS5a (HCV NS5a Produkte)

Substanzklasse: Viral Protein

Hintergrund:

Synonyms: HCV, HCV Non-structural protein 5A, Non-structural protein 5A, NS5a, p56, HCV NS5a, POLG_HCVBK.

Background: HCV is classified into the genus Hepacivirus of the family Flaviviridae. Like all the members of the family, HCV is an enveloped, single-stranded, positive-sense RNA virus. Its genome (about 9600 nt) is flanked at both termini by conserved, highly structured non-translated regions (NTRs) and encodes a polyprotein precursor (about 3000 aa), which is proteolytically processed by host and viral proteases to produce the structural (core, E1, E2 and p7) and non-structural (NS2, NS3, NS4A, NS4B, NS5A and NS5B) proteins of the virus. Recently, an additional protein has been identified, whose function remains unknown. NS5A is a ~56 kDa pleiotropic protein with key roles in both viral RNA replication and modulation of the physiology of the host cell.

UniProt: Q14SZ0