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HHAT Antikörper (AA 101-200) (AbBy Fluor® 594)

HHAT Reaktivität: Human WB, IF (p), IF (cc) Wirt: Kaninchen Polyclonal AbBy Fluor® 594
Produktnummer ABIN2814325
  • Target Alle HHAT Antikörper anzeigen
    HHAT (Hedgehog Acyltransferase (HHAT))
    Bindungsspezifität
    • 14
    • 10
    • 7
    • 6
    • 1
    AA 101-200
    Reaktivität
    • 32
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 32
    Kaninchen
    Klonalität
    • 32
    Polyklonal
    Konjugat
    • 9
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser HHAT Antikörper ist konjugiert mit AbBy Fluor® 594
    Applikation
    • 32
    • 14
    • 12
    • 12
    • 12
    • 12
    • 5
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    Homologie
    Human,Mouse,Rat
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human HHAT
    Isotyp
    IgG
    Top Product
    Discover our top product HHAT Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    HHAT (Hedgehog Acyltransferase (HHAT))
    Andere Bezeichnung
    HHAT (HHAT Produkte)
    Synonyme
    RGD1311746 antikoerper, MART2 antikoerper, SKI1 antikoerper, Skn antikoerper, 2810432O22Rik antikoerper, AI462858 antikoerper, AP-2CRE antikoerper, Tg(TFAP2A-cre)1Will antikoerper, hedgehog acyltransferase antikoerper, Hhat antikoerper, HHAT antikoerper, hhat antikoerper
    Hintergrund

    Synonyms: 2810432O22Rik, AC115917.1, AI462858, FLJ10724, FLJ34867, Hedgehog acyltransferase, Hhat, HHAT_HUMAN, MART 2, MART-2, MART2, Melanoma antigen recognized by T cells 2, Melanoma antigen recognized by T-cells 2, MGC11697, OTTMUSP00000033669, Protein cysteine N palmitoyltransferase HHAT, Protein-cysteine N-palmitoyltransferase HHAT, RGD1311746, SKI1, Skinny hedgehog protein 1, Skinny hedgehog protein, Skn.

    Background: HHAT is a 493 amino acid multi-pass membrane protein that localizes to the endoplasmic reticulum and belongs to the membrane-bound acyltransferase family. Expressed ubiquitously, HHAT functions to catalyze the N-terminal palmitoylation of SSH (slingshot homolog), an event that is required for SHH signaling pathways. HHAT is expressed in cancer cell lines, suggesting a role for HHAT in tumorigenesis. The gene encoding HHAT maps to human chromosome 1 and is expressed as four alternatively spliced isoforms. Chromosome 1 is the largest human chromosome, spanning about 260 million base pairs and making up 8 % of the human genome. Several disorders, including Stickler syndrome, Parkinsons Disease, Gaucher disease, malignant melanoma and Usher syndrome, are caused by defects in genes that localize to chromosome 1.

    Gen-ID
    55733
    Pathways
    Hedgehog Signalweg
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