HIV-1 gp120
Reaktivität: Human Immunodeficiency Virus (HIV)
WB, IHC, EIA
Wirt: Ziege
Polyclonal
Peroxidase (POD)
Applikationshinweise
ELISA: 1:2,000, IHC: 1:200 Optimal conditions should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
Lot specific
Buffer
Supplied as a liquid in PBS.
Handhabung
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Lagerung
-80 °C
Informationen zur Lagerung
Aliquot and store at -70 °C or lower.
Kondo, Melikyan: "Intercellular adhesion molecule 1 promotes HIV-1 attachment but not fusion to target cells." in: PLoS ONE, Vol. 7, Issue 9, pp. e44827, (2013) (PubMed).
Miyauchi, Curran, Long, Kondo, Iwamoto, Engelman, Matsuda: "The membrane-spanning domain of gp41 plays a critical role in intracellular trafficking of the HIV envelope protein." in: Retrovirology, Vol. 7, pp. 95, (2010) (PubMed).
Human immunodeficiency virus (HIV) is a lentivirus that causes acquired immunodeficiency syndrome (AIDS), a condition in humans in which the immune system begins to fail, leading to life-threatening opportunistic infections. Envelope glycoprotein GP120 (or gp120) is a glycoprotein exposed on the surface of the HIV envelope. The 120 in its name comes from its molecular weight of 120 kilodaltons. gp120 is essential for virus entry into cells as it plays a vital role in seeking out specific cell surface receptors for entry.