ATM Antikörper (C-Term)

Produktnummer ABIN363380

Produktdetails anti-ATM Antikörper

Target: ATM (Ataxia Telangiectasia Mutated (ATM))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Spezifität: Reacts with human and mouse ATM protein

Aufreinigung: Antigen affinity purified

Immunogen: A fragment of human ATM protein expressed in E.coli. The fragment relates to the C-terminal region (within the last third of the protein sequence)

Anwendungsinformationen

Applikationshinweise:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
- ICC/IF : 1/100 - IP : 1/100 to 1/500 - WB : 1/500 to 1/1 000 - IHC: 1/100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 2.5 mg/mL

Buffer: PBS, glycerol 50 % , Sodium azide 0.05 %

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C/-80 °C

Informationen zur Lagerung: Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.

Details zu ATM

Target: ATM (Ataxia Telangiectasia Mutated (ATM))

Andere Bezeichnung: Serine-Protein Kinase ATM (ATM Produkte)

Hintergrund: Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Involved in Cell cycle, DNA damage, DNA repair.

Gen-ID: 472

Pathways: p53 Signalweg, Apoptose, DNA Reparatur, Inositol Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus