Sca-1/Ly-6A/E Antikörper (Biotin)

Produktnummer ABIN2853588

Der Ratte Monoklonal anti-Sca-1/Ly-6A/E Antikörper wird verwendet zum Nachweis von Sca-1/Ly-6A/E in Proben von Maus. Er wurde validiert für FACS.

Kurzübersicht für Sca-1/Ly-6A/E Antikörper (Biotin) (ABIN2853588)

Target: Sca-1/Ly-6A/E (Ly6a) (Lymphocyte Antigen 6 Complex, Locus A (Ly6a))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser Sca-1/Ly-6A/E Antikörper ist konjugiert mit Biotin

Applikation: Flow Cytometry (FACS)

Klon: 238B

Produktdetails anti-Sca-1/Ly-6A/E Antikörper (Biotin)

Spezifität: This antibody reacts withSca-1.

Kreuzreaktivität (Details): Species reactivity (tested):Mouse

Aufreinigung: Protein-G agarose

Immunogen: Mouse Sca-1 transfected LO cells

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, 0.09 % NaN3, 1 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2 - 8 °C.

Details zu Sca-1/Ly-6A/E

Target: Sca-1/Ly-6A/E (Ly6a) (Lymphocyte Antigen 6 Complex, Locus A (Ly6a))

Andere Bezeichnung: Ly6A/E / SCA1

Hintergrund: Sca-1 is a member of the Ly-6 antigen family which molecular mass of 8 kDa under non-reducing conditions and of 18 kDa under reducing conditions. Mouse hematopoietic stem cells express low levels of Thy-1 antigen (Thy-1lo) and to be negative for lineage markers (Lin-) that is, not expressing markers characteristic of B cells (B220), granulocytes (Gr-1), myelomonocytic cells (Mac-1) and T lymphocytes (CD4 and CD8). Recently, new monoclonal antibody, anti-Sca-1, was used to purify stem cells from the Thy-1lo, Linbone marrow subpopulation. Thy-1lo, Lin-, Sca-1+ (but not the Thy-1lo, Lin-, Sca-1-) population of bone marrow cells are highly purified pluripotent stem cells. They read out with nearly unit efficiency in assays for primitive myeloerythroid and thymic progenitor, and have a capability to admit lethally irradiated mouse to survive and be restored in all blood-cell lineages. The Thy-1lo, Lin-, Sca-1+ subpopulation thought to have all stem cells present in the bone marrow.Synonyms: Ly-6A.2/Ly-6E.1, Lymphocyte antigen 6A-2/6E-1, SCA-1, Stem cell antigen 1, T-cell-activating protein, TAP

Gen-ID: 110454

NCBI Accession: NP_034868

UniProt: P05533

Pathways: Sensory Perception of Sound, Activated T Cell Proliferation