Septin 2 Antikörper

Produktnummer ABIN2854352

Produktdetails anti-Septin 2 Antikörper

Target: Septin 2 (SEPT2)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Septin 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human

Produktmerkmale: Rabbit Polyclonal antibody to Septin 2 (septin 2)
Septin 2 antibody

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Septin 2. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: U87-MG , SK-N-SH

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu Septin 2

Target: Septin 2 (SEPT2)

Andere Bezeichnung: septin 2 (SEPT2 Produkte)

Synonyme: DIFF6 antikoerper, NEDD5 antikoerper, Pnutl3 antikoerper, hNedd5 antikoerper, AW208991 antikoerper, Nedd-5 antikoerper, Nedd5 antikoerper, mKIAA0158 antikoerper, Vesp11 antikoerper, nedd5 antikoerper, wu:fb52g01 antikoerper, wu:fb99a01 antikoerper, Septin-2A antikoerper, Septin-A antikoerper, diff6 antikoerper, pnutl3 antikoerper, sept2 antikoerper, septa antikoerper, xlsepta antikoerper, SEPT2 antikoerper, Sep-02 antikoerper, Septin-2B antikoerper, hnedd5 antikoerper, sept2-B antikoerper, Septin-2 antikoerper, septin 2 antikoerper, septin 2 L homeolog antikoerper, septin 2-like antikoerper, COG1487; VapC; putative nucleic acid-binding protein; contains PIN domain antikoerper, septin 2 S homeolog antikoerper, SEPT2 antikoerper, Sept2 antikoerper, sept2 antikoerper, sept2.L antikoerper, SEPT2L antikoerper, sepT2 antikoerper, sept2.S antikoerper

Hintergrund: Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis. Forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, may be required for chromosome segregation and spindle elongation. May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri.

Cellular Localization: Cytoplasm , Spindle

Molekulargewicht: 41 kDa

Gen-ID: 4735

UniProt: Q15019