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RAP1A Antikörper (Center)

RAP1A Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2854404
  • Target Alle RAP1A Antikörper anzeigen
    RAP1A (RAP1A, Member of RAS Oncogene Family (RAP1A))
    Bindungsspezifität
    • 15
    • 10
    • 8
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    Reaktivität
    • 47
    • 47
    • 17
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 56
    • 5
    Kaninchen
    Klonalität
    • 57
    • 4
    Polyklonal
    Konjugat
    • 25
    • 5
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser RAP1A Antikörper ist unkonjugiert
    Applikation
    • 48
    • 24
    • 13
    • 13
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Kreuzreaktivität
    Maus, Ratte (Rattus), Rhesusaffen, Rind (Kuh)
    Kreuzreaktivität (Details)
    Mouse (100 %), Rat (100 %), Rhesus Monkey (100 %), Bovine (100 %)
    Produktmerkmale
    Rabbit polyclonal antibody to RAP1A (RAP1A, member of RAS oncogene family)
    RAP1 antibody
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human RAP1. The exact sequence is proprietary.
    Isotyp
    IgG
    Top Product
    Discover our top product RAP1A Primärantikörper
  • Applikationshinweise
    Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*
    Kommentare

    Positive Control: 293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.53 mg/mL
    Buffer
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    Konservierungsmittel
    Thimerosal (Merthiolate)
    Vorsichtsmaßnahmen
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Chinigò, Grolez, Audero, Bokhobza, Bernardini, Cicero, Toillon, Bailleul, Visentin, Ruffinatti, Brysbaert, Lensink, De Ruyck, Cantelmo, Fiorio Pla, Gkika: "TRPM8-Rap1A Interaction Sites as Critical Determinants for Adhesion and Migration of Prostate and Other Epithelial Cancer Cells." in: Cancers, Vol. 14, Issue 9, (2022) (PubMed).

  • Target
    RAP1A (RAP1A, Member of RAS Oncogene Family (RAP1A))
    Andere Bezeichnung
    RAP1 (RAP1A Produkte)
    Synonyme
    KREV-1 antikoerper, KREV1 antikoerper, RAP1 antikoerper, SMGP21 antikoerper, AI848598 antikoerper, G-22K antikoerper, Krev-1 antikoerper, Rap1 antikoerper, RAP-1A antikoerper, rap 1A antikoerper, wu:fc66g06 antikoerper, zgc:86676 antikoerper, krev-1 antikoerper, krev1 antikoerper, rap1 antikoerper, RAP1A, member of RAS oncogene family antikoerper, RAS-related protein 1a antikoerper, RAP1A, member of RAS oncogene family a antikoerper, RAP1A, member of RAS oncogene family L homeolog antikoerper, RAP1A antikoerper, Rap1a antikoerper, rap1aa antikoerper, rap1a.L antikoerper
    Hintergrund
    The product of this gene belongs to the family of RAS-related proteins. These proteins share approximately 50 % amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between RAP proteins and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. The product of this gene counteracts the mitogenic function of RAS because it can interact with RAS GAPs and RAF in a competitive manner. Two transcript variants encoding the same protein have been identified for this gene.

    Cellular Localization: Cell membrane, Lipid-anchor
    Molekulargewicht
    21 kDa
    Gen-ID
    5906
    Pathways
    T-Zell Rezeptor Signalweg, Neurotrophin Signalübertragung, Signaling of Hepatocyte Growth Factor Receptor
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