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LIG1 Antikörper (C-Term)

LIG1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2854412
  • Target Alle LIG1 Antikörper anzeigen
    LIG1 (Ligase I, DNA, ATP-Dependent (LIG1))
    Bindungsspezifität
    • 13
    • 7
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 63
    • 16
    • 9
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 55
    • 9
    • 1
    Kaninchen
    Klonalität
    • 48
    • 17
    Polyklonal
    Konjugat
    • 36
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser LIG1 Antikörper ist unkonjugiert
    Applikation
    • 44
    • 29
    • 15
    • 8
    • 8
    • 7
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Kreuzreaktivität
    Human
    Produktmerkmale
    Rabbit polyclonal antibody to DNA ligase I (ligase I, DNA, ATP-dependent)
    DNA ligase I antibody [C2C3], C-term
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the C-terminus region of human DNA ligase I. The exact sequence is proprietary.
    Isotyp
    IgG
    Top Product
    Discover our top product LIG1 Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Kommentare

    Positive Control: A431 , H1299

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Konservierungsmittel
    Thimerosal (Merthiolate)
    Vorsichtsmaßnahmen
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Liddiard, Ruis, Kan, Cleal, Ashelford, Hendrickson, Baird: "DNA Ligase 1 is an essential mediator of sister chromatid telomere fusions in G2 cell cycle phase." in: Nucleic acids research, Vol. 47, Issue 5, pp. 2402-2424, (2019) (PubMed).

  • Target
    LIG1 (Ligase I, DNA, ATP-Dependent (LIG1))
    Andere Bezeichnung
    DNA ligase 1 (LIG1 Produkte)
    Synonyme
    ATLIG1 antikoerper, DNA ligase 1 antikoerper, T6D22.23 antikoerper, ligI antikoerper, AL033288 antikoerper, LigI antikoerper, lig1 antikoerper, wu:fc54a11 antikoerper, DNA ligase 1 antikoerper, DNA ligase 1, putative antikoerper, ligase I, DNA, ATP-dependent L homeolog antikoerper, ligase I, DNA, ATP-dependent antikoerper, LIG1 antikoerper, PB000674.02.0 antikoerper, PTRG_06243 antikoerper, PKH_140260 antikoerper, lig1.L antikoerper, Lig1 antikoerper, lig-1 antikoerper, lig1 antikoerper
    Hintergrund
    LIG1 encodes DNA ligase I, with functions in DNA replication and the base excision repair process. Mutations in LIG1 that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents.

    Cellular Localization: Nucleus
    Molekulargewicht
    102 kDa
    Gen-ID
    3978
    UniProt
    P18858
    Pathways
    Telomere Maintenance, DNA Reparatur, DNA Replication, Synthesis of DNA
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