nectin-3 Antikörper (Center)

Produktnummer ABIN2854443

Produktdetails anti-nectin-3 Antikörper

Target: nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))

Bindungsspezifität: Center

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser nectin-3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Maus, Ratte (Rattus)

Kreuzreaktivität (Details): Mouse (94 %), Rat (94 %)

Produktmerkmale: Rabbit polyclonal antibody to Nectin 3 (poliovirus receptor-related 3)
Nectin 3 antibody

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Nectin 3. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference Western blot 1:1000-1:10000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:1000-1:10000*

Kommentare:

Positive Control: K562 , THP-1

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu nectin-3

Target: nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))

Andere Bezeichnung: Nectin 3 (NECTIN3 Produkte)

Synonyme: PVRL3 antikoerper, CD113 antikoerper, CDW113 antikoerper, NECTIN-3 antikoerper, PPR3 antikoerper, PRR3 antikoerper, PVRR3 antikoerper, 2610301B19Rik antikoerper, 3000002N23Rik antikoerper, 4921513D19Rik antikoerper, AA407785 antikoerper, AU016832 antikoerper, AW538082 antikoerper, nectin cell adhesion molecule 3 antikoerper, poliovirus receptor-related 3 antikoerper, Nectin3 antikoerper, NECTIN3 antikoerper, PVRL3 antikoerper, nectin3 antikoerper

Hintergrund: Nectins (e.g., PVRL1, MIM 600644) are immunoglobulin-like adhesion molecules that interact with afadin (AF6, MIM 159559). Afadin is an actin filament-binding protein that connects nectins to the actin cytoskeleton. The nectin-afadin system organizes adherens junctions cooperatively with the cadherin (see MIM 192090)-catenin (see MIM 116805) system in epithelial cells.[supplied by OMIM]

Cellular Localization: Cell membrane, Single-pass membrane protein

Molekulargewicht: 61 kDa

Gen-ID: 25945

Pathways: Cell-Cell Junction Organization