FBXW2 Antikörper (C-Term)

Produktnummer ABIN2854490

Produktdetails anti-FBXW2 Antikörper

Target: FBXW2 (F-Box and WD Repeat Domain Containing 2 (FBXW2))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FBXW2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Human

Produktmerkmale: Rabbit polyclonal antibody to FBXW2 (F-box and WD repeat domain containing 2)
FBXW2 antibody

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human FBXW2. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: A431

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu FBXW2

Target: FBXW2 (F-Box and WD Repeat Domain Containing 2 (FBXW2))

Andere Bezeichnung: F-box and WD repeat domain containing 2 (FBXW2 Produkte)

Synonyme: FBXW2 antikoerper, md6 antikoerper, fbw2 antikoerper, fwd2 antikoerper, MGC53244 antikoerper, FBW2 antikoerper, Fwd2 antikoerper, Md6 antikoerper, wu:fc72f10 antikoerper, zgc:110365 antikoerper, 2700071L08Rik antikoerper, MD6 antikoerper, F-box and WD repeat domain containing 2 antikoerper, F-box and WD repeat domain containing 2 L homeolog antikoerper, F-box and WD-40 domain protein 2 antikoerper, FBXW2 antikoerper, fbxw2 antikoerper, Fbxw2 antikoerper, fbxw2.L antikoerper

Hintergrund: F-box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif, the F box. Some F-box proteins have been shown to be critical for the ubiquitin-mediated degradation of cellular regulatory proteins. In fact, F-box proteins are one of the four subunits of ubiquitin protein ligases, called SCFs. SCF ligases bring ubiquitin conjugating enzymes to substrates that are specifically recruited by the different F-box proteins. Mammalian F-box proteins are classified into three groups based on the presence of either WD-40 repeats, leucine-rich repeats, or the presence or absence of other protein-protein interacting domains. This gene encodes the second identified member of the F-box gene family and contains multiple WD-40 repeats.

Molekulargewicht: 52 kDa

Gen-ID: 26190

UniProt: Q9UKT8