CHRNA3 Antikörper (Center)

Produktnummer ABIN2854522

Produktdetails anti-CHRNA3 Antikörper

Target: CHRNA3 (Cholinergic Receptor, Nicotinic, alpha 3 (Neuronal) (CHRNA3))

Bindungsspezifität: Center

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CHRNA3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Kreuzreaktivität: Maus, Huhn, Ratte (Rattus), Rind (Kuh)

Kreuzreaktivität (Details): Mouse (94 %), Chicken (87 %), Rat (94 %), Bovine (96 %)

Produktmerkmale: Rabbit Polyclonal antibody to AChR alpha 3
AChR alpha 3 antibody

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Nicotinic Acetylcholine Receptor alpha 3. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference ICC/IF 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* Western blot1:500-1:3000*

Kommentare:

Positive Control: Molt-4

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu CHRNA3

Target: CHRNA3 (Cholinergic Receptor, Nicotinic, alpha 3 (Neuronal) (CHRNA3))

Andere Bezeichnung: AChR alpha 3 (CHRNA3 Produkte)

Synonyme: LNCR2 antikoerper, NACHRA3 antikoerper, PAOD2 antikoerper, (a)3 antikoerper, A730007P14Rik antikoerper, Acra-3 antikoerper, Acra3 antikoerper, cholinergic receptor nicotinic alpha 3 subunit antikoerper, cholinergic receptor, nicotinic, alpha polypeptide 3 antikoerper, CHRNA3 antikoerper, Chrna3 antikoerper

Hintergrund: This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described.

Cellular Localization: Cell junction , synapse , postsynaptic cell membrane , Cell membrane

Molekulargewicht: 57 kDa

Gen-ID: 1136

Pathways: Synaptic Membrane