RAD51 Homolog B Antikörper (Center)

Produktnummer ABIN2854538

Produktdetails anti-RAD51 Homolog B Antikörper

Target: RAD51 Homolog B (Rad51B)

Bindungsspezifität: Center

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAD51 Homolog B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Maus, Rind (Kuh)

Kreuzreaktivität (Details): Mouse (86 %), Bovine (91 %)

Produktmerkmale: Rabbit polyclonal antibody to RAD51L1 (RAD51-like 1 (S. cerevisiae))
RAD51B antibody [N1C3]

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human RAD51B. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*

Kommentare:

Positive Control: Raji

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu RAD51 Homolog B

Target: RAD51 Homolog B (Rad51B)

Andere Bezeichnung: RAD51L1 (Rad51B Produkte)

Hintergrund: The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed.

Cellular Localization: Nucleus

Molekulargewicht: 42 kDa

Gen-ID: 5890

Pathways: DNA Reparatur