PDIA3 Antikörper (C-Term)

Produktnummer ABIN2854699

Produktdetails anti-PDIA3 Antikörper

Target: PDIA3 (Protein Disulfide Isomerase Family A, Member 3 (PDIA3))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDIA3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Rabbit Polyclonal antibody to ERp57 (protein disulfide isomerase family A, member 3)
ERp57 antibody [C3], C-term

Aufreinigung: Affinity purified by Protein A.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human ERp57. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: NIH-3T3 , JC , BCL-1 , H1299 , HeLa , HepG2

Validation: Comparison

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu PDIA3

Target: PDIA3 (Protein Disulfide Isomerase Family A, Member 3 (PDIA3))

Andere Bezeichnung: protein disulfide isomerase family A member 3 (PDIA3 Produkte)

Synonyme: ER60 antikoerper, ERp57 antikoerper, ERp60 antikoerper, ERp61 antikoerper, GRP57 antikoerper, GRP58 antikoerper, HsT17083 antikoerper, P58 antikoerper, PI-PLC antikoerper, grp-58 antikoerper, 58kDa antikoerper, Erp antikoerper, Grp58 antikoerper, PDI antikoerper, PDI-Q2 antikoerper, PLC[a] antikoerper, Plca antikoerper, 1 antikoerper, 25D3-membrane-associated antikoerper, sb:cb825 antikoerper, erp57 antikoerper, grp58 antikoerper, pdia3 antikoerper, protein disulfide isomerase family A member 3 antikoerper, protein disulfide-isomerase A3 antikoerper, protein disulfide isomerase associated 3 antikoerper, protein disulfide isomerase family A, member 3 antikoerper, protein disulfide isomerase family A member 3 S homeolog antikoerper, PDIA3 antikoerper, Tsp_10062 antikoerper, Pdia3 antikoerper, pdia3 antikoerper, pdia3.S antikoerper

Hintergrund: This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase, however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates.

Cellular Localization: Endoplasmic reticulum lumen (By similarity) , Melanosome

Molekulargewicht: 57 kDa

Gen-ID: 2923

UniProt: P30101

Pathways: Maintenance of Protein Location, Protein targeting to Nucleus, Cell RedoxHomeostasis