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ADRA2C Antikörper (C-Term)

ADRA2C Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2854717
  • Target Alle ADRA2C Antikörper anzeigen
    ADRA2C (Adrenergic, alpha-2C-, Receptor (ADRA2C))
    Bindungsspezifität
    • 23
    • 23
    • 16
    • 10
    • 8
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 82
    • 47
    • 20
    • 7
    • 4
    • 4
    • 2
    • 1
    Human
    Wirt
    • 59
    • 26
    Kaninchen
    Klonalität
    • 59
    • 26
    Polyklonal
    Konjugat
    • 31
    • 6
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ADRA2C Antikörper ist unkonjugiert
    Applikation
    • 55
    • 25
    • 20
    • 17
    • 15
    • 14
    • 13
    • 13
    • 11
    • 11
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Human
    Produktmerkmale
    Rabbit Polyclonal antibody to alpha 2c Adrenergic Receptor (adrenergic, alpha-2C-, receptor)
    alpha 2c Adrenergic Receptor antibody [C2C3], C-term
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Immunogen
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human alpha 2c Adrenergic Receptor. The exact sequence is proprietary.
    Isotyp
    IgG
    Top Product
    Discover our top product ADRA2C Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Kommentare

    Positive Control: HeLa

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.62 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Konservierungsmittel
    Thimerosal (Merthiolate)
    Vorsichtsmaßnahmen
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    ADRA2C (Adrenergic, alpha-2C-, Receptor (ADRA2C))
    Andere Bezeichnung
    adrenoceptor alpha 2C (ADRA2C Produkte)
    Synonyme
    ADRA2L2 antikoerper, ADRA2RL2 antikoerper, ADRARL2 antikoerper, ALPHA2CAR antikoerper, Adra-2c antikoerper, [a]2C antikoerper, alpha2-C4 antikoerper, alpha2C antikoerper, zgc:194523 antikoerper, zgc:194541 antikoerper, adra2c antikoerper, ADRA2B antikoerper, ADRA2C antikoerper, adrenoceptor alpha 2C antikoerper, adrenergic receptor, alpha 2c antikoerper, ADRA2C antikoerper, Adra2c antikoerper, adra2c antikoerper
    Hintergrund
    Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences.

    Cellular Localization: Cell membrane
    Molekulargewicht
    50 kDa
    Gen-ID
    152
    UniProt
    P18825
    Pathways
    EGFR Signaling Pathway, cAMP Metabolic Process
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