CXCR1 Antikörper (C-Term)

Produktnummer ABIN2854740

Produktdetails anti-CXCR1 Antikörper

Target: CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CXCR1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus

Produktmerkmale: Rabbit Polyclonal antibody to CXCR1 (chemokine (C-X-C motif) receptor 1)
CXCR1 antibody [C2C3], C-term

Aufreinigung: Purified by antigen-affinity chromatography.

Güteklasse: KO Validated

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human CXCR1. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Validation: KO/KD

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.97 mg/mL

Buffer: 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu CXCR1

Target: CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))

Andere Bezeichnung: C-X-C motif chemokine receptor 1 (CXCR1 Produkte)

Synonyme: C-C antikoerper, C-C-CKR-1 antikoerper, CD128 antikoerper, CD181 antikoerper, CDw128a antikoerper, CKR-1 antikoerper, CMKAR1 antikoerper, IL8R1 antikoerper, IL8RA antikoerper, IL8RBA antikoerper, Il8ra antikoerper, CXCR-1 antikoerper, IL-8RA antikoerper, CXCR2 antikoerper, IL8RB antikoerper, cxcr1 antikoerper, cxcr2 antikoerper, C-X-C motif chemokine receptor 1 antikoerper, chemokine (C-X-C motif) receptor 1 antikoerper, C-X-C chemokine receptor type 1 antikoerper, C-X-C motif chemokine receptor 1 S homeolog antikoerper, CXCR1 antikoerper, Cxcr1 antikoerper, LOC100461947 antikoerper, cxcr1.S antikoerper

Hintergrund: The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36.

Cellular Localization: Cell membrane

Molekulargewicht: 40 kDa

Gen-ID: 3577

UniProt: P25024

Pathways: cAMP Metabolic Process