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MTDH Antikörper

MTDH Reaktivität: Human WB, IF, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2854801
  • Target Alle MTDH Antikörper anzeigen
    MTDH (Metadherin (MTDH))
    Reaktivität
    • 49
    • 18
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 40
    • 7
    • 3
    Kaninchen
    Klonalität
    • 45
    • 5
    Polyklonal
    Konjugat
    • 28
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MTDH Antikörper ist unkonjugiert
    Applikation
    • 40
    • 15
    • 13
    • 13
    • 11
    • 10
    • 8
    • 8
    • 6
    • 4
    • 2
    • 2
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Rabbit polyclonal antibody to LYRIC (metadherin)
    LYRIC antibody [N2C3]
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human LYRIC . The exact sequence is proprietary.
    Isotyp
    IgG
  • Applikationshinweise
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Kommentare

    Positive Control: rat brain

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.69 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Konservierungsmittel
    Thimerosal (Merthiolate)
    Vorsichtsmaßnahmen
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Lai, Chuang, Liu, Ho, Lin, Anderson, Yeh: "Antibodies Against Modified NS1 Wing Domain Peptide Protect Against Dengue Virus Infection." in: Scientific reports, Vol. 7, Issue 1, pp. 6975, (2019) (PubMed).

  • Target
    MTDH (Metadherin (MTDH))
    Andere Bezeichnung
    metadherin (MTDH Produkte)
    Synonyme
    MGC75963 antikoerper, 2610103J23Rik antikoerper, 3D3 antikoerper, 3D3/Lyric antikoerper, AEG-1 antikoerper, AV353288 antikoerper, D8Bwg1112e antikoerper, Lyric antikoerper, AEG1 antikoerper, LYRIC antikoerper, LYRIC/3D3 antikoerper, metadherin antikoerper, mtdh antikoerper, MTDH antikoerper, Mtdh antikoerper
    Hintergrund
    Downregulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Activates the nuclear factor kappa-B (NF-kappa-B) transcription factor. Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion. Promotes lung metastasis and also has an effect on bone and brain metastasis, possibly by enhancing the seeding of tumor cells to the target organ endothelium. Induces chemoresistance.

    Cellular Localization: Endoplasmic reticulum membrane, Single-pass membrane protein , Nucleus membrane, Single-pass membrane protein (By similarity) , Cell junction , tight junction (By similarity) , Nucleus , nucleolus (By similarity) , Cytoplasm , perinuclear region
    Molekulargewicht
    64 kDa
    Gen-ID
    92140
    UniProt
    Q86UE4
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization
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