SOD1 Antikörper (C-Term)
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- Target Alle SOD1 Antikörper anzeigen
- SOD1 (Superoxide Dismutase 1, Soluble (SOD1))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SOD1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
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Rabbit Polyclonal antibody to SOD1 (superoxide dismutase 1, soluble)
SOD1 antibody - Aufreinigung
- Purified by antigen-affinity chromatography.
- Güteklasse
- KO Validated
- Immunogen
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human SOD1. The exact sequence is proprietary.
- Isotyp
- IgG
- Top Product
- Discover our top product SOD1 Primärantikörper
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- Applikationshinweise
- WB: 1:500-1:10000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Kommentare
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Positive Control: Rat brain , 293T , A431 , HeLa , HepG2
Validation: KO/KD, Orthogonal
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.21 mg/mL
- Buffer
- 1XPBS pH 7, 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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Exogenous C₈-Ceramide Induces Apoptosis by Overproduction of ROS and the Switch of Superoxide Dismutases SOD1 to SOD2 in Human Lung Cancer Cells." in: International journal of molecular sciences, Vol. 19, Issue 10, (2019) (PubMed).
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Exogenous C₈-Ceramide Induces Apoptosis by Overproduction of ROS and the Switch of Superoxide Dismutases SOD1 to SOD2 in Human Lung Cancer Cells." in: International journal of molecular sciences, Vol. 19, Issue 10, (2019) (PubMed).
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- Target
- SOD1 (Superoxide Dismutase 1, Soluble (SOD1))
- Andere Bezeichnung
- superoxide dismutase 1 (SOD1 Produkte)
- Hintergrund
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The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.
Cellular Localization: Cytoplasm - Molekulargewicht
- 16 kDa
- Gen-ID
- 6647
- UniProt
- P00441
- Pathways
- Sensory Perception of Sound, Transition Metal Ion Homeostasis
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