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MMP3 Antikörper

MMP3 Reaktivität: Human WB, ICC, IF, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2854847
  • Target Alle MMP3 Antikörper anzeigen
    MMP3 (Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3))
    Reaktivität
    • 132
    • 52
    • 48
    • 18
    • 5
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 111
    • 38
    • 2
    • 1
    • 1
    Kaninchen
    Klonalität
    • 104
    • 49
    Polyklonal
    Konjugat
    • 91
    • 12
    • 11
    • 10
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MMP3 Antikörper ist unkonjugiert
    Applikation
    • 110
    • 67
    • 62
    • 30
    • 28
    • 22
    • 16
    • 13
    • 13
    • 11
    • 9
    • 7
    • 5
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Human
    Produktmerkmale
    Rabbit Polyclonal antibody to MMP3 (matrix metallopeptidase 3 (stromelysin 1, progelatinase))
    MMP3 antibody [N3C1], Internal
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Immunogen
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human MMP3. The exact sequence is proprietary.
    Isotyp
    IgG
    Top Product
    Discover our top product MMP3 Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Kommentare

    Validation: Orthogonal

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Konservierungsmittel
    Thimerosal (Merthiolate)
    Vorsichtsmaßnahmen
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Kim, Choi, Lee, Soh, Kim, Park: "Senescent tumor cells lead the collective invasion in thyroid cancer." in: Nature communications, Vol. 8, pp. 15208, (2018) (PubMed).

  • Target
    MMP3 (Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3))
    Andere Bezeichnung
    matrix metallopeptidase 3 (MMP3 Produkte)
    Synonyme
    CHDS6 antikoerper, MMP-3 antikoerper, SL-1 antikoerper, STMY antikoerper, STMY1 antikoerper, STR1 antikoerper, SLN-1 antikoerper, SLN1 antikoerper, STR-1 antikoerper, Stmy1 antikoerper, Str1 antikoerper, MMP10 antikoerper, chds6 antikoerper, mmp-3 antikoerper, mmp13 antikoerper, mmp3 antikoerper, sl-1 antikoerper, stmy antikoerper, stmy1 antikoerper, str1 antikoerper, matrix metallopeptidase 3 antikoerper, matrix metallopeptidase 3 (stromelysin 1, progelatinase) antikoerper, matrix metallopeptidase 3 L homeolog antikoerper, MMP3 antikoerper, Mmp3 antikoerper, mmp3.L antikoerper
    Hintergrund
    Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

    Cellular Localization: Secreted , extracellular space , extracellular matrix
    Molekulargewicht
    54 kDa
    Gen-ID
    4314
    UniProt
    P08254
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