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RAC1 Antikörper (Center)

Name: RAC1 Antikörper (Center)
Brand: antibodies-online
SKU: ABIN2854858
Price: 659.23 EUR
Availability: InStock

Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

WB Image Sample (30 ug of whole cell lysate) A: Hela B: Raji 12% SDS PAGE antibody diluted at 1:1000 (RAC1 Antikörper (Center))

IHC-P Image Immunohistochemical analysis of paraffin-embedded H441 xenograft , using RAC1, antibody at 1:100 dilution. (RAC1 Antikörper (Center))

IHC

WB Image Sample (50 ug of whole cell lysate) A: mouse liver 12% SDS PAGE antibody diluted at 1:1000 (RAC1 Antikörper (Center))

STAT3 signaling is downstream of Rac activity during invasion of human breast cancer(A) Immunohistochemistry shows that Rac1 protein expression (left panel) and STAT3 phosphorylation on Ser727 (right panel) frequently coincide in human breast cancer. (RAC1 Antikörper (Center))

IHC

C/EBPδ represses RhoA expression and contributes to attenuated migration of IL-1β-treated astrocytes. (RAC1 Antikörper (Center))

5 Abbildungen

(2 Referenzen)

Produktnummer ABIN2854858

Datenblatt (PDF)

Target Alle RAC1 Antikörper anzeigen

RAC1
Bindungsspezifität
18

15

10

5

4

3

2

2

2

1

1

1

1

1

1
Center
Reaktivität
82

52

38

5

4

4

4

4

4

4

4

3

3

2

1

1

1
Human, Maus
Wirt
73

8

1
Kaninchen
Passende Sekundärantikörper
Klonalität
73

9
Polyklonal
Konjugat
35

5

5

5

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1
Dieser RAC1 Antikörper ist unkonjugiert
Applikation
56

26

26

22

15

10

9

5

3

2

1

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität

Huhn, Hund, Schwein, Ratte (Rattus), Xenopus laevis, Rind (Kuh), Xenopus tropicalis

Kreuzreaktivität (Details)

Chicken (90 %), Dog (90 %), Pig (90 %), Rat (90 %), Xenopus laevis (90 %), Bovine (90 %), Xenopus tropicalis (90 %)

Produktmerkmale

Rabbit Polyclonal antibody to RAC1 (ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1))
RAC1 antibody

Aufreinigung

Purified by antigen-affinity chromatography.

Immunogen

Recombinant protein encompassing a sequence within the center region of human RAC1. The exact sequence is proprietary.

Isotyp

IgG
anti-RAC1 (AA 1-192) antibody
Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-RAC1 antibody
Reaktivität: Human, Ratte WB, ELISA, IHC, FACS Wirt: Maus Monoclonal 1301CT276-121-104 unconjugated

anti-RAC1 (AA 11-185) antibody
Reaktivität: Human ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-RAC1 antibody
Reaktivität: Human, Ratte WB, IHC (p), FACS Wirt: Maus Monoclonal 1301CT276-121-104 unconjugated

anti-RAC1 (pSer71) antibody
Reaktivität: Human, Maus, Ratte WB, IF (cc), IF (p), IHC (p) Wirt: Kaninchen Polyclonal unconjugated

anti-RAC1 (AA 49-78) antibody
Reaktivität: Human, Ratte WB Wirt: Kaninchen Polyclonal RB11123 unconjugated

anti-RAC1 antibody
Reaktivität: Human, Maus, Ratte, Hund, Huhn WB, IHC, IF, IP Wirt: Maus Monoclonal 102-Rac1 unconjugated

anti-RAC1 (AA 101-192) antibody
Reaktivität: Human, Maus ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-RAC1 antibody
Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Maus Monoclonal 13C4 unconjugated

anti-RAC1 (AA 100-192) antibody (Biotin)
Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal Biotin

Applikationshinweise

Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Kommentare

Positive Control: 293T , A431 , HeLa , HepG2 , Molt-4 , Raji , mouse liver

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 mg/mL

Buffer

0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel

Thimerosal (Merthiolate)

Vorsichtsmaßnahmen

This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

-20 °C

Informationen zur Lagerung

Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Wang, Hsu, Ko, Chiu, Kan, Lai, Wang: "Astrocytic CCAAT/Enhancer-Binding Protein Delta Contributes to Glial Scar Formation and Impairs Functional Recovery After Spinal Cord Injury." in: Molecular neurobiology, Vol. 53, Issue 9, pp. 5912-5927, (2018) (PubMed).

Katz, Sims, Sproul, Caldwell, Dixon, Meehan, Harrison: "Targeting of Rac GTPases blocks the spread of intact human breast cancer." in: Oncotarget, Vol. 3, Issue 6, pp. 608-19, (2012) (PubMed).
Target

RAC1

Abstract

RAC1 Produkte

Hintergrund

The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene.

Cellular Localization: Cell membrane, Lipid-anchor, Cytoplasmic side (By similarity) , Melanosome

Molekulargewicht

21 kDa

Gen-ID

5879

Pathways

WNT Signalweg, Regulation of Actin Filament Polymerization, Cell-Cell Junction Organization, Thromboxane A2 Receptor Signaling, VEGF Signaling