RAC1 Antikörper (Center)

Produktnummer ABIN2854858

Produktdetails anti-RAC1 Antikörper

Target: RAC1

Bindungsspezifität: Center

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Huhn, Hund, Schwein, Ratte (Rattus), Xenopus laevis, Rind (Kuh), Xenopus tropicalis

Kreuzreaktivität (Details): Chicken (90 %), Dog (90 %), Pig (90 %), Rat (90 %), Xenopus laevis (90 %), Bovine (90 %), Xenopus tropicalis (90 %)

Produktmerkmale: Rabbit Polyclonal antibody to RAC1 (ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1))
RAC1 antibody

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human RAC1. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Kommentare:

Positive Control: 293T , A431 , HeLa , HepG2 , Molt-4 , Raji , mouse liver

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Referenzen für anti-RAC1 Antikörper (ABIN2854858)

Wang, Hsu, Ko, Chiu, Kan, Lai, Wang: "Astrocytic CCAAT/Enhancer-Binding Protein Delta Contributes to Glial Scar Formation and Impairs Functional Recovery After Spinal Cord Injury." in: Molecular neurobiology, Vol. 53, Issue 9, pp. 5912-5927, (2018) (PubMed).

Katz, Sims, Sproul, Caldwell, Dixon, Meehan, Harrison: "Targeting of Rac GTPases blocks the spread of intact human breast cancer." in: Oncotarget, Vol. 3, Issue 6, pp. 608-19, (2012) (PubMed).

Details zu RAC1

Target: RAC1

Abstract: RAC1 Produkte

Synonyme: Rac-1 antikoerper, TC-25 antikoerper, p21-Rac1 antikoerper, AL023026 antikoerper, D5Ertd559e antikoerper, RAC2 antikoerper, CRAC1A antikoerper, rac1 antikoerper, wu:fd16e02 antikoerper, zgc:55823 antikoerper, zgc:55917 antikoerper, zgc:86934 antikoerper, 2248 antikoerper, CG2248 antikoerper, D-Rac antikoerper, D-Rac 1 antikoerper, D-Rac1 antikoerper, DRac antikoerper, DRac1 antikoerper, DRacA antikoerper, Dm Rac1 antikoerper, DmRAC antikoerper, DmRAC1 antikoerper, Dmel\CG2248 antikoerper, Dmrac1 antikoerper, Drac antikoerper, Drac1 antikoerper, Drac1a antikoerper, DracA antikoerper, GTPase Rac1 antikoerper, P40792 antikoerper, RAC1 antikoerper, Rac antikoerper, Rac GTPase antikoerper, Rac3 antikoerper, RacA antikoerper, dRac antikoerper, dRac1 antikoerper, drac1 antikoerper, rac antikoerper, Xrac antikoerper, mig5 antikoerper, p21-rac1 antikoerper, tc-25 antikoerper, Rac family small GTPase 1 antikoerper, RAS-related C3 botulinum substrate 1 antikoerper, ras-related C3 botulinum toxin substrate 1 antikoerper, ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) antikoerper, Rac family small GTPase 1a antikoerper, CG2248 gene product from transcript CG2248-RB antikoerper, Rac family small GTPase 1 L homeolog antikoerper, ras homolog family member G antikoerper, RAC1 antikoerper, Rac1 antikoerper, rac1a antikoerper, rac1.L antikoerper, RHOG antikoerper

Hintergrund: The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene.

Cellular Localization: Cell membrane, Lipid-anchor, Cytoplasmic side (By similarity) , Melanosome

Molekulargewicht: 21 kDa

Gen-ID: 5879

Pathways: WNT Signalweg, Regulation of Actin Filament Polymerization, Cell-Cell Junction Organization, Thromboxane A2 Receptor Signaling, VEGF Signaling