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RPSA/Laminin Receptor Antikörper

RPSA Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2854873
  • Target Alle RPSA/Laminin Receptor (RPSA) Antikörper anzeigen
    RPSA/Laminin Receptor (RPSA) (Ribosomal Protein SA (RPSA))
    Reaktivität
    • 52
    • 30
    • 24
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    Human
    Wirt
    • 42
    • 11
    Kaninchen
    Klonalität
    • 33
    • 19
    Polyklonal
    Konjugat
    • 33
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser RPSA/Laminin Receptor Antikörper ist unkonjugiert
    Applikation
    • 32
    • 16
    • 10
    • 8
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Human, Maus
    Produktmerkmale
    Rabbit Polyclonal antibody to RPSA (ribosomal protein SA)
    RPSA antibody [N1C3]
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human RPSA. The exact sequence is proprietary.
    Isotyp
    IgG
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  • Applikationshinweise
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Kommentare

    Positive Control: Mouse brain , Jurkat , HepG2

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.1 mg/mL
    Buffer
    1XPBS pH 7, 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    RPSA/Laminin Receptor (RPSA) (Ribosomal Protein SA (RPSA))
    Andere Bezeichnung
    ribosomal protein SA (RPSA Produkte)
    Synonyme
    37LRP antikoerper, 67LR antikoerper, LBP/p40 antikoerper, LRP/LR antikoerper, LamR antikoerper, rpsa antikoerper, LamR1 antikoerper, RPSA antikoerper, LAMBR antikoerper, LAMR1 antikoerper, LBP antikoerper, LRP antikoerper, NEM/1CHD4 antikoerper, SA antikoerper, lamR antikoerper, p40 antikoerper, 67kDa antikoerper, 67lr antikoerper, AL022858 antikoerper, Lamr antikoerper, Lamr1 antikoerper, Lamrl1 antikoerper, MLR antikoerper, P40 antikoerper, P40-3 antikoerper, P40-8 antikoerper, lamr1 antikoerper, zgc:55831 antikoerper, zgc:77824 antikoerper, DMRT1 antikoerper, 40S ribosomal protein SA antikoerper, 67kD laminin receptor antikoerper, ribosomal protein SA antikoerper, rssa antikoerper, rpsa antikoerper, RPSA antikoerper, Rpsa antikoerper, LOC100144340 antikoerper
    Hintergrund
    Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. This receptor has been variously called 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP) and p40 ribosome-associated protein. The amino acid sequence of laminin receptor 1 is highly conserved through evolution, suggesting a key biological function. It has been observed that the level of the laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype. Multiple copies of this gene exist, however, most of them are pseudogenes thought to have arisen from retropositional events. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.

    Cellular Localization: Cell membrane , Cytoplasm (By similarity) , Nucleus (By similarity)
    Molekulargewicht
    33 kDa
    Gen-ID
    3921
    UniProt
    P08865
    Pathways
    Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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