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Angiopoietin 2 Antikörper

ANGPT2 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2854896
  • Target Alle Angiopoietin 2 (ANGPT2) Antikörper anzeigen
    Angiopoietin 2 (ANGPT2)
    Reaktivität
    • 72
    • 36
    • 26
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 74
    • 10
    • 4
    • 1
    • 1
    • 1
    Kaninchen
    Klonalität
    • 67
    • 24
    Polyklonal
    Konjugat
    • 45
    • 10
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Angiopoietin 2 Antikörper ist unkonjugiert
    Applikation
    • 61
    • 31
    • 31
    • 13
    • 13
    • 10
    • 10
    • 9
    • 6
    • 6
    • 4
    • 4
    • 3
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Human, Maus
    Produktmerkmale
    Rabbit Polyclonal antibody to Angiopoietin 2 (angiopoietin-2)
    Angiopoietin 2 antibody
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human Angiopoietin 2. The exact sequence is proprietary.
    Isotyp
    IgG
    Top Product
    Discover our top product ANGPT2 Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Kommentare

    Validation: Orthogonal

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1.04 mg/mL
    Buffer
    1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Gu, Zhang, Han, Gao, Cui, Sun, Niu, You, Huang, Chang, Wang, Yeh: "Targeting the ERβ/Angiopoietin-2/Tie-2 signaling-mediated angiogenesis with the FDA-approved anti-estrogen Faslodex to increase the Sunitinib sensitivity in RCC." in: Cell death & disease, Vol. 11, Issue 5, pp. 367, (2020) (PubMed).

    Fischer, Seifen, Baer, Jung, Mertens, Scheller, Zacharowski, Hofmann, Maier, Urbschat: "The Fibrin Cleavage Product Bβ15-42 Channels Endothelial and Tubular Regeneration in the Post-acute Course During Murine Renal Ischemia Reperfusion Injury." in: Frontiers in pharmacology, Vol. 9, pp. 369, (2018) (PubMed).

  • Target
    Angiopoietin 2 (ANGPT2)
    Andere Bezeichnung
    angiopoietin 2 (ANGPT2 Produkte)
    Synonyme
    AGPT2 antikoerper, ANG2 antikoerper, Agpt2 antikoerper, Ang-2 antikoerper, Ang2 antikoerper, ang2 antikoerper, angpt2 antikoerper, ANGIOPOIETIN-2 antikoerper, ANG-2 antikoerper, ANGPT2 antikoerper, Angrp antikoerper, Rnase5b antikoerper, ANG3 antikoerper, C11orf2 antikoerper, C11orf3 antikoerper, FFR antikoerper, angiopoietin 2 antikoerper, angiopoietin 2b antikoerper, angiogenin, ribonuclease A family, member 2 antikoerper, VPS51, GARP complex subunit antikoerper, ANGPT2 antikoerper, Angpt2 antikoerper, angpt2b antikoerper, Ang2 antikoerper, VPS51 antikoerper
    Hintergrund
    The protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE-2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene.

    Cellular Localization: Secreted
    Molekulargewicht
    57 kDa
    Gen-ID
    285
    UniProt
    O15123
    Pathways
    RTK Signalweg
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