Prosaposin Antikörper

Produktnummer ABIN2854916

Produktdetails anti-Prosaposin Antikörper

Target: Prosaposin (PSAP)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Prosaposin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Rabbit polyclonal antibody to PSAP (prosaposin)
PSAP antibody [N1N3]

Aufreinigung: Purified by antigen-affinity chromatography.

Güteklasse: KO Validated

Immunogen: Recombinant protein encompassing a sequence within the center region of human PSAP. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: mouse brain , rat brain , HeLa

Validation: KO/KD

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.98 mg/mL

Buffer: 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu Prosaposin

Target: Prosaposin (PSAP)

Andere Bezeichnung: prosaposin (PSAP Produkte)

Synonyme: GLBA antikoerper, SAP1 antikoerper, AI037048 antikoerper, SGP-1 antikoerper, SGP1A antikoerper, cb759 antikoerper, wu:fa14a06 antikoerper, wu:fb36e02 antikoerper, wu:fb58g07 antikoerper, PSAP antikoerper, PSP-A antikoerper, SFTPA1B antikoerper, SP-A antikoerper, prosaposin antikoerper, surfactant protein A1 antikoerper, PSAP antikoerper, Psap antikoerper, psap antikoerper, LOC100011417 antikoerper, LOC100304726 antikoerper, LOC100526719 antikoerper, SFTPA1 antikoerper

Hintergrund: This gene encodes a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease, Tay-Sachs disease, and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.

Cellular Localization: Lysosome

Molekulargewicht: 58 kDa

Gen-ID: 5660

UniProt: P07602

Pathways: Positive Regulation of Endopeptidase Activity