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ube3a Antikörper

ube3a Reaktivität: Human IF, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2854930
  • Target Alle ube3a Antikörper anzeigen
    ube3a (Ubiquitin Protein Ligase E3A (ube3a))
    Reaktivität
    • 51
    • 12
    • 8
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 46
    • 5
    Kaninchen
    Klonalität
    • 46
    • 5
    Polyklonal
    Konjugat
    • 28
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ube3a Antikörper ist unkonjugiert
    Applikation
    • 28
    • 17
    • 16
    • 13
    • 13
    • 8
    • 8
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Rabbit Polyclonal antibody to UBE3A (ubiquitin protein ligase E3A)
    UBE3A antibody
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human UBE3A. The exact sequence is proprietary.
    Isotyp
    IgG
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  • Applikationshinweise
    ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1.26 mg/mL
    Buffer
    1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    ube3a (Ubiquitin Protein Ligase E3A (ube3a))
    Andere Bezeichnung
    ubiquitin protein ligase E3A (ube3a Produkte)
    Synonyme
    ANCR antikoerper, AS antikoerper, E6-AP antikoerper, EPVE6AP antikoerper, HPVE6A antikoerper, DDBDRAFT_0188760 antikoerper, DDBDRAFT_0302447 antikoerper, DDB_0188760 antikoerper, DDB_0302447 antikoerper, ube3a antikoerper, im:7140733 antikoerper, zgc:92173 antikoerper, 4732496B02 antikoerper, 5830462N02Rik antikoerper, A130086L21Rik antikoerper, Hpve6a antikoerper, mKIAA4216 antikoerper, As antikoerper, CG6190 antikoerper, Dmel\\CG6190 antikoerper, Dube3a antikoerper, UBE3A antikoerper, dUBE3A antikoerper, das antikoerper, dube3A antikoerper, dube3a antikoerper, MGC69536 antikoerper, UME3A antikoerper, ubiquitin protein ligase E3A antikoerper, ubiquitin-protein ligase E3A antikoerper, Ubiquitin protein ligase E3A antikoerper, ubiquitin protein ligase E3A (human papilloma virus E6-associated protein, Angelman syndrome) S homeolog antikoerper, ubiquitin protein ligase E3A (human papilloma virus E6-associated protein, Angelman syndrome) antikoerper, UBE3A antikoerper, ube3a antikoerper, LOC100194730 antikoerper, Ube3a antikoerper, ube3a.S antikoerper, Eint_040430 antikoerper
    Hintergrund
    This gene encodes an E3 ubiquitin-protein ligase, part of the ubiquitin protein degradation system. This imprinted gene is maternally expressed in brain and biallelically expressed in other tissues. Maternally inherited deletion of this gene causes Angelman Syndrome, characterized by severe motor and intellectual retardation, ataxia, hypotonia, epilepsy, absence of speech, and characteristic facies. The protein also interacts with the E6 protein of human papillomavirus types 16 and 18, resulting in ubiquitination and proteolysis of tumor protein p53. Alternative splicing of this gene results in three transcript variants encoding three isoforms with different N-termini. Additional transcript variants have been described, but their full length nature has not been determined.

    Cellular Localization: Nucleus
    Molekulargewicht
    100 kDa
    Gen-ID
    7337
    UniProt
    Q05086
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway
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