POR Antikörper (C-Term)

Produktnummer ABIN2854937

Produktdetails anti-POR Antikörper

Target: POR (P450 (Cytochrome) Oxidoreductase (POR))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus

Produktmerkmale: Rabbit Polyclonal antibody to POR (P450 (cytochrome) oxidoreductase)
POR antibody [C2C3], C-term

Aufreinigung: Purified by antigen-affinity chromatography.

Güteklasse: KO Validated

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human POR. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: HepG2 , Mouse liver , HeLa

Validation: KO/KD

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.73 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu POR

Target: POR (P450 (Cytochrome) Oxidoreductase (POR))

Andere Bezeichnung: cytochrome p450 oxidoreductase (POR Produkte)

Synonyme: CPR antikoerper, CYPOR antikoerper, P450R antikoerper, POR antikoerper, CCR antikoerper, CG11567 antikoerper, DMR antikoerper, DmCPR antikoerper, Dmel\\CG11567 antikoerper, NCPR antikoerper, P450 antikoerper, cpr antikoerper, zgc:110032 antikoerper, npr antikoerper, xpor antikoerper, 4933424M13Rik antikoerper, PORCINO antikoerper, T5J17.90 antikoerper, T5J17_90 antikoerper, TFC C antikoerper, TUBULIN-FOLDING COFACTOR C antikoerper, cytochrome p450 oxidoreductase antikoerper, P450 (cytochrome) oxidoreductase antikoerper, ADP-ribosylation factor interacting protein 2 antikoerper, Cytochrome P450 reductase antikoerper, P450 (cytochrome) oxidoreductase a antikoerper, P450 (cytochrome) oxidoreductase L homeolog antikoerper, NADPH--cytochrome P450 reductase antikoerper, C-CAP/cofactor C-like domain-containing protein antikoerper, POR antikoerper, Arfip2 antikoerper, Por antikoerper, Cpr antikoerper, pora antikoerper, por.L antikoerper, LOC100406157 antikoerper, por antikoerper, LOC100619047 antikoerper

Hintergrund: This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.

Cellular Localization: Endoplasmic reticulum membrane, Peripheral membrane protein

Molekulargewicht: 77 kDa

Gen-ID: 5447

UniProt: P16435

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, SARS-CoV-2 Protein Interaktom