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Insulin Receptor Antikörper (C-Term)

Name: Insulin Receptor Antikörper (C-Term)
Brand: antibodies-online
SKU: ABIN2854945
Price: 659.23 EUR
Availability: InStock

KO Validated INSR Reaktivität: Human WB, ICC, IF, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

WB Image Insulin Receptor beta subunit antibody detects Insulin Receptor beta subunit protein by western blot analysis. (Insulin Receptor Antikörper (C-Term))

IHC-P Image Insulin Receptor antibody detects Insulin Receptor protein at membrane on mouse prostate by immunohistochemical analysis. (Insulin Receptor Antikörper (C-Term))

IHC

IHC-P Image Insulin Receptor antibody detects INSR protein at cytosol on human gastric cancer by immunohistochemical analysis. (Insulin Receptor Antikörper (C-Term))

IHC

WB Image Sample (30 ug of whole cell lysate) A: NIH-3T3 5% SDS PAGE antibody diluted at 1:1000 (Insulin Receptor Antikörper (C-Term))

4 Abbildungen

Produktnummer ABIN2854945

Datenblatt (PDF)

Target Alle Insulin Receptor (INSR) Antikörper anzeigen

Insulin Receptor (INSR)
Bindungsspezifität
16

14

13

10

8

8

7

5

5

5

5

4

4

4

4

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
C-Term
Reaktivität
172

89

78

17

11

9

8

7

6

6

4

3

2

2

1

1

1

1

1

1

1

1
Human
Wirt
158

29

2

1
Kaninchen
Passende Sekundärantikörper
Klonalität
146

44
Polyklonal
Konjugat
123

14

14

5

5

4

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser Insulin Receptor Antikörper ist unkonjugiert
Applikation
134

76

53

34

20

16

14

14

13

13

9

5

4

4

3

2

2

2

1

1

1

1

1

1
Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität

Human, Maus, Ratte, Zebrafisch (Danio rerio)

Produktmerkmale

Rabbit Polyclonal antibody to Insulin Receptor (insulin receptor)
Insulin Receptor antibody

Aufreinigung

Purified by antigen-affinity chromatography.

Güteklasse

KO Validated

Immunogen

Recombinant protein encompassing a sequence within the C-terminus region of human Insulin Receptor. The exact sequence is proprietary.

Isotyp

IgG

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anti-Insulin Receptor (INSR) (AA 27-57), (N-Term) antibody
INSR Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB1421 unconjugated

anti-Insulin Receptor (INSR) (AA 28-57), (N-Term) antibody
INSR Reaktivität: Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB01419 unconjugated

Applikationshinweise

WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare

Positive Control: NIH-3T3 , PC-12 , rat liver
Validation: KO/KD

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1.31 mg/mL

Buffer

1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

Konservierungsmittel

ProClin

Vorsichtsmaßnahmen

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Target

Insulin Receptor (INSR)

Andere Bezeichnung

insulin receptor (INSR Produkte)

Hintergrund

After removal of the precursor signal peptide, the insulin receptor precursor is post-translationally cleaved into two chains (alpha and beta) that are covalently linked. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Two transcript variants encoding different isoforms have been found for this gene.

Cellular Localization: Membrane, Single-pass type I membrane protein

Molekulargewicht

156 kDa

Gen-ID

3643

UniProt

P06213

Pathways

NF-kappaB Signalweg, RTK Signalweg, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity