MLH1 Antikörper
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- Target Alle MLH1 Antikörper anzeigen
- MLH1 (MutL Homolog 1 (MLH1))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MLH1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Kreuzreaktivität
- Human
- Produktmerkmale
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Rabbit Polyclonal antibody to MLH1 (mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli))
MLH1 antibody - Aufreinigung
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human MLH1. The exact sequence is proprietary.
- Isotyp
- IgG
- Top Product
- Discover our top product MLH1 Primärantikörper
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- Applikationshinweise
- WB: 1:500-1:20000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Kommentare
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Positive Control: A549 , H1299 , human MLH1-transfected 293T
Validation: Overexpression
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.94 mg/mL
- Buffer
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
- Konservierungsmittel
- Thimerosal (Merthiolate)
- Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- MLH1 (MutL Homolog 1 (MLH1))
- Andere Bezeichnung
- mutL homolog 1 (MLH1 Produkte)
- Synonyme
- CG11482 antikoerper, Dmel\\CG11482 antikoerper, dmlh-1 antikoerper, dmlh1 antikoerper, zgc:66301 antikoerper, MLH1 antikoerper, LOC100232198 antikoerper, 1110035C23Rik antikoerper, AI317206 antikoerper, AI325952 antikoerper, AI561766 antikoerper, COCA2 antikoerper, FCC2 antikoerper, HNPCC antikoerper, HNPCC2 antikoerper, hMLH1 antikoerper, mutL homolog 1 antikoerper, CG11482 gene product from transcript CG11482-RB antikoerper, mutL homolog 1 S homeolog antikoerper, mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) antikoerper, DNA mismatch repair protein Mlh1 antikoerper, MLH1 antikoerper, Mlh1 antikoerper, mlh1.S antikoerper, mlh1 antikoerper, LOC588545 antikoerper
- Hintergrund
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This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Alternatively spliced transcript variants encoding different isoforms have been described, but their full-length natures have not been determined.
Cellular Localization: Nucleus - Molekulargewicht
- 85 kDa
- Gen-ID
- 4292
- UniProt
- P40692
- Pathways
- DNA Reparatur, Production of Molecular Mediator of Immune Response
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