Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

FLNB Antikörper (N-Term)

KO Validated FLNB Reaktivität: Human WB, IF, ICC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2854971
  • Target Alle FLNB Antikörper anzeigen
    FLNB (Filamin B, beta (FLNB))
    Bindungsspezifität
    • 15
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 43
    • 8
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 38
    • 4
    • 1
    Kaninchen
    Klonalität
    • 40
    • 3
    Polyklonal
    Konjugat
    • 26
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FLNB Antikörper ist unkonjugiert
    Applikation
    • 40
    • 13
    • 13
    • 11
    • 8
    • 8
    • 8
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Human, Maus
    Produktmerkmale
    Rabbit Polyclonal antibody to Filamin B (filamin B, beta)
    Filamin B antibody [N1], N-term
    Aufreinigung
    Affinity purified by Protein A.
    Güteklasse
    KO Validated
    Immunogen
    Recombinant protein encompassing a sequence within the N-terminus region of human Filamin B. The exact sequence is proprietary.
    Isotyp
    IgG
    Top Product
    Discover our top product FLNB Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Kommentare

    Positive Control: U87-MG , NIH-3T3 , 293T , A431 , HeLa , HepG2

    Validation: KO/KD

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    10 mg/mL
    Buffer
    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
    Konservierungsmittel
    Thimerosal (Merthiolate)
    Vorsichtsmaßnahmen
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Artym, Swatkoski, Matsumoto, Campbell, Petrie, Dimitriadis, Li, Mueller, Bugge, Gucek, Yamada: "Dense fibrillar collagen is a potent inducer of invadopodia via a specific signaling network." in: The Journal of cell biology, Vol. 208, Issue 3, pp. 331-50, (2015) (PubMed).

  • Target
    FLNB (Filamin B, beta (FLNB))
    Andere Bezeichnung
    filamin B (FLNB Produkte)
    Synonyme
    ABP-278 antikoerper, ABP-280 antikoerper, AOI antikoerper, FH1 antikoerper, FLN-B antikoerper, FLN1L antikoerper, LRS1 antikoerper, SCT antikoerper, TABP antikoerper, TAP antikoerper, AL024016 antikoerper, filamin B antikoerper, filamin, beta antikoerper, FLNB antikoerper, Flnb antikoerper
    Hintergrund
    This gene encodes a member of the filamin family. The encoded protein interacts with glycoprotein Ib alpha as part of the process to repair vascular injuries. The platelet glycoprotein Ib complex includes glycoprotein Ib alpha, and it binds the actin cytoskeleton. Mutations in this gene have been found in several conditions: atelosteogenesis type 1 and type 3, boomerang dysplasia, autosomal dominant Larsen syndrome, and spondylocarpotarsal synostosis syndrome. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.

    Cellular Localization: Isoform 1: Cytoplasm , cell cortex , Cytoplasm , cytoskeleton , myofibril , sarcomere , Z-disk , Isoform 2: Cytoplasm , Isoform 3: Cytoplasm , Isoform 6: Cytoplasm
    Molekulargewicht
    278 kDa
    Gen-ID
    2317
    UniProt
    O75369
    Pathways
    Maintenance of Protein Location
Sie sind hier:
Kundenservice