EIF2A Antikörper (Center)

Produktnummer ABIN2854984

Produktdetails anti-EIF2A Antikörper

Target: EIF2A (Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A))

Bindungsspezifität: Center

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EIF2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Kreuzreaktivität: Rhesusaffen

Kreuzreaktivität (Details): Rhesus Monkey (100 %)

Produktmerkmale: Rabbit Polyclonal antibody to eIF2 alpha (eukaryotic translation initiation factor 2, subunit 1 alpha, 35 kDa)
eIF2 alpha antibody [N1C3]

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human eIF2 alpha. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference ICC/IF 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* Western blot1:500-1:3000*

Kommentare:

Positive Control: H1299 , Raji , *rat neuron , *HeLa , *N2a ,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.31 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Referenzen für anti-EIF2A Antikörper (ABIN2854984)

Wu, Yen, Kou, Wu: "Luteolin and Apigenin Attenuate 4-Hydroxy-2-Nonenal-Mediated Cell Death through Modulation of UPR, Nrf2-ARE and MAPK Pathways in PC12 Cells." in: PLoS ONE, Vol. 10, Issue 6, pp. e0130599, (2016) (PubMed).

Details zu EIF2A

Target: EIF2A (Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A))

Andere Bezeichnung: eIF2 alpha (EIF2A Produkte)

Synonyme: ATEIF2-A2 antikoerper, EIF2-A2 antikoerper, eukaryotic translation initiation factor 2 alpha subunit antikoerper, EIF-2A antikoerper, MST089 antikoerper, MSTP004 antikoerper, MSTP089 antikoerper, D030048D22 antikoerper, D3Ertd194e antikoerper, im:7145971 antikoerper, zgc:110460 antikoerper, DDBDRAFT_0185936 antikoerper, DDBDRAFT_0234177 antikoerper, DDB_0185936 antikoerper, DDB_0234177 antikoerper, Eif2a antikoerper, eif2a antikoerper, eif2alpha antikoerper, EIF2A antikoerper, CG9946 antikoerper, Dmel\\CG9946 antikoerper, Eif2alpha antikoerper, IF2A_DROME antikoerper, M(1)14C antikoerper, M(1)19-153 antikoerper, M(1)8e3-10 antikoerper, deIF2alpha antikoerper, eIF-2 antikoerper, eIF-2 a antikoerper, eIF-2 alpha antikoerper, eIF2 alpha antikoerper, eIF2-alpha antikoerper, eIF2a antikoerper, eIF2alpha antikoerper, eiF-2alpha antikoerper, elF2alpha antikoerper, l(1)14Cf antikoerper, l(1)19-153 antikoerper, eukaryotic translation initiation factor 2 alpha subunit antikoerper, eukaryotic translation initiation factor 2A antikoerper, eukaryotic translation initiation factor 2A, 65kDa antikoerper, eukaryotic translation initiation factor 2A S homeolog antikoerper, eukaryotic translation initiation factor antikoerper, eukaryotic translation Initiation Factor 2alpha antikoerper, EIF2 ALPHA antikoerper, EIF2A antikoerper, Eif2a antikoerper, eif2a antikoerper, eIF2a antikoerper, eif2a.S antikoerper, eif2A antikoerper, eIF-2alpha antikoerper

Hintergrund: The translation initiation factor eIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, eIF2, and GTP. eIF2 is composed of 3 nonidentical subunits, alpha (36 kD), beta (38 kD, MIM 603908), and gamma (52 kD, MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of eIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM]

Molekulargewicht: 36 kDa

Gen-ID: 1965

Pathways: Ribonucleoprotein Complex Subunit Organization, ER-Nucleus Signaling, Hepatitis C, Methionine Biosynthetic Process, Ribosome Assembly