GBA Antikörper (C-Term)

Produktnummer ABIN2854995

Produktdetails anti-GBA Antikörper

Target: GBA (Glucosidase, Beta, Acid (GBA))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GBA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Kreuzreaktivität: Schimpanse

Kreuzreaktivität (Details): Chimpanzee (100 %)

Produktmerkmale: Rabbit Polyclonal antibody to GBA (glucosidase, beta, acid)
GBA antibody [C1C3]

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human GBA. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Kommentare:

Positive Control: 293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.82 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu GBA

Target: GBA (Glucosidase, Beta, Acid (GBA))

Andere Bezeichnung: GBA (GBA Produkte)

Synonyme: GBA1 antikoerper, GCB antikoerper, GLUC antikoerper, BETA-GLUCOSIDASE antikoerper, T12J13.8 antikoerper, T12J13_8 antikoerper, beta glucosidase 25 antikoerper, PSPTO3318 antikoerper, PSPTO4290 antikoerper, GC antikoerper, GCase antikoerper, betaGC antikoerper, glucosylceramidase beta antikoerper, beta glucosidase 25 antikoerper, beta-glucosidase antikoerper, Beta-glucosidase antikoerper, glucosidase, beta, acid antikoerper, glucosylceramidase antikoerper, bglX-2 antikoerper, GBA antikoerper, BGLU25 antikoerper, PSPTO_3318 antikoerper, bglX antikoerper, bglA4 antikoerper, Gba antikoerper, LOC100399524 antikoerper, bglA.2 antikoerper, bglX-2 antikoerper

Hintergrund: This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants encoding the same protein.

Cellular Localization: Lysosome membrane, Peripheral membrane protein, Lumenal side

Molekulargewicht: 60 kDa

Gen-ID: 2629

Pathways: Cellular Glucan Metabolic Process