BLM Antikörper (C-Term)

Produktnummer ABIN2855003

Produktdetails anti-BLM Antikörper

Target: BLM (Bloom Syndrome RecQ Like Helicase (BLM))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BLM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Produktmerkmale: Rabbit Polyclonal antibody to BLM (Bloom syndrome, RecQ helicase-like)
BLM antibody [C3], C-term

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human BLM. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Kommentare:

Positive Control: Jurkat , Raji , K562 , NCI-H929 , NIH-3T3 , JC , BCL-1

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.35 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu BLM

Target: BLM (Bloom Syndrome RecQ Like Helicase (BLM))

Andere Bezeichnung: BLM (BLM Produkte)

Synonyme: BS antikoerper, RECQ2 antikoerper, RECQL2 antikoerper, RECQL3 antikoerper, blm-A antikoerper, xBLM antikoerper, ORF1 antikoerper, Bloom syndrome RecQ like helicase antikoerper, Bloom syndrome RecQ like helicase S homeolog antikoerper, Bloom syndrome, RecQ like helicase antikoerper, BLM antikoerper, blm.S antikoerper, Blm antikoerper

Hintergrund: The Bloom syndrome gene product is related to the RecQ subset of DExH box-containing DNA helicases and has both DNA-stimulated ATPase and ATP-dependent DNA helicase activities. Mutations causing Bloom syndrome delete or alter helicase motifs and may disable the 3'-5' helicase activity. The normal protein may act to suppress inappropriate recombination.

Cellular Localization: Nucleus

Molekulargewicht: 159 kDa

Gen-ID: 641

Pathways: DNA Reparatur