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CSTB Antikörper

CSTB Reaktivität: Human IF, ICC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2855050
  • Target Alle CSTB Antikörper anzeigen
    CSTB (Cystatin B (Stefin B) (CSTB))
    Reaktivität
    • 85
    • 21
    • 20
    • 9
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Human
    Wirt
    • 85
    • 17
    • 1
    • 1
    Kaninchen
    Klonalität
    • 84
    • 19
    Polyklonal
    Konjugat
    • 48
    • 15
    • 8
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CSTB Antikörper ist unkonjugiert
    Applikation
    • 65
    • 38
    • 35
    • 15
    • 13
    • 13
    • 12
    • 12
    • 8
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Human, Maus
    Produktmerkmale
    Rabbit Polyclonal antibody to Cystatin B (cystatin B (stefin B))
    Cystatin B antibody
    Aufreinigung
    Affinity purified by Protein A.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human Cystatin B. The exact sequence is proprietary.
    Isotyp
    IgG
    Top Product
    Discover our top product CSTB Primärantikörper
  • Applikationshinweise
    ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    6.04 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Konservierungsmittel
    Thimerosal (Merthiolate)
    Vorsichtsmaßnahmen
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    CSTB (Cystatin B (Stefin B) (CSTB))
    Andere Bezeichnung
    cystatin B (CSTB Produkte)
    Hintergrund
    The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1).

    Cellular Localization: Cytoplasm , Nucleus
    Molekulargewicht
    11 kDa
    Gen-ID
    1476
    UniProt
    P04080
    Pathways
    Response to Water Deprivation
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