COX IV Antikörper (Center)

Produktnummer ABIN2855069

Produktdetails anti-COX IV Antikörper

Target: COX IV (COX4I1) (Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1))

Bindungsspezifität: Center

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COX IV Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Kreuzreaktivität: Schimpanse

Kreuzreaktivität (Details): Chimpanzee (100 %)

Produktmerkmale: Rabbit Polyclonal antibody to COX4 (cytochrome c oxidase subunit IV isoform 1)
COX4 antibody

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human COX4. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Immunoprecipitation 1:100-1:500* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Immunoprecipitation1:100-1:500* Western blot1:500-1:3000*

Kommentare:

Positive Control: 293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.38 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu COX IV

Target: COX IV (COX4I1) (Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1))

Andere Bezeichnung: COX4 (COX4I1 Produkte)

Synonyme: COX4 antikoerper, COX4-1 antikoerper, COXIV antikoerper, mg:bb02d03 antikoerper, zgc:110058 antikoerper, GB20012 antikoerper, AL024441 antikoerper, Cox4 antikoerper, Cox4a antikoerper, cox4 antikoerper, cox4i1 antikoerper, coxiv antikoerper, BcDNA:AT07685 antikoerper, CG10396 antikoerper, COX IV antikoerper, CX41 antikoerper, CX42 antikoerper, Dmel\CG10396 antikoerper, IV antikoerper, cytochrome c oxidase subunit 4I1 antikoerper, cytochrome c oxidase subunit IV isoform 1 antikoerper, cytochrome c oxidase subunit 4 isoform 1, mitochondrial antikoerper, cytochrome c oxidase polypeptide IV antikoerper, cytochrome c oxidase subunit IV antikoerper, cytochrome c oxidase subunit 4i1 antikoerper, cytochrome c oxidase subunit IV isoform 1 S homeolog antikoerper, Cytochrome c oxidase subunit 4-like antikoerper, COX4I1 antikoerper, cox4i1 antikoerper, LOC412396 antikoerper, Cox4I1 antikoerper, LOC780848 antikoerper, BMEII0322 antikoerper, RSal33209_1582 antikoerper, SJAG_00976 antikoerper, HMPREF0733_11926 antikoerper, Cox4i1 antikoerper, cox4i1.S antikoerper, COX4L antikoerper

Hintergrund: Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it.

Cellular Localization: Mitochondrion inner membrane

Molekulargewicht: 20 kDa

Gen-ID: 1327

Pathways: Proton Transport