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GRK2 Antikörper (C-Term)

Name: GRK2 Antikörper (C-Term)
Brand: antibodies-online
SKU: ABIN2855125
Price: 630.63 EUR
Availability: InStock

KO Validated ADRBK1 Reaktivität: Human WB, IHC (p), IF, ICC, FACS, IP Wirt: Kaninchen Polyclonal unconjugated

WB Image Sample (30 ug of whole cell lysate) A:NIH-3T3 7. (GRK2 Antikörper (C-Term))

WB Image GRK2 antibody detects GRK2 protein by western blot analysis. (GRK2 Antikörper (C-Term))

ICC/IF Image Confocal immunofluorescence analysis (Olympus FV10i) of methanol-fixed HeLa, using GRK2, antibody (Green) at 1:100 dilution. (GRK2 Antikörper (C-Term))

WB Image Sample(30 ug whole cell lysate) A:MOLT4 , 7. (GRK2 Antikörper (C-Term))

IP Image Immunoprecipitation of GRK2 protein from Jurkat whole cell extracts using 5 μg of GRK2 antibody [C2C3], C-term, Western blot analysis was performed using GRK2 antibody [C2C3], C-term, EasyBlot anti-Rabbit IgG was used as a secondary reagent. (GRK2 Antikörper (C-Term))

IHC-P Image Immunohistochemical analysis of paraffin-embedded OVCAR3 xenograft, using GRK2, antibody at 1:500 dilution. (GRK2 Antikörper (C-Term))

IHC

6 Abbildungen

Produktnummer ABIN2855125

Datenblatt (PDF)

Target Alle GRK2 (ADRBK1) Antikörper anzeigen

GRK2 (ADRBK1) (Adrenergic, Beta, Receptor Kinase 1 (ADRBK1))
Bindungsspezifität
16

11

10

7

6

6

5

4

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
C-Term
Reaktivität
101

80

59

9

7

6

5

4

4

2

2

1
Human
Wirt
94

9

2

2
Kaninchen
Passende Sekundärantikörper
Klonalität
90

17
Polyklonal
Konjugat
61

7

6

4

3

3

3

3

3

3

1

1

1

1

1

1

1

1

1

1

1
Dieser GRK2 Antikörper ist unkonjugiert
Applikation
58

46

34

18

14

13

4

4

3

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunoprecipitation (IP)

Kreuzreaktivität

Human, Maus

Produktmerkmale

Rabbit Polyclonal antibody to GRK2 (adrenergic, beta, receptor kinase 1)
GRK2 antibody [C2C3], C-term

Aufreinigung

Purified by antigen-affinity chromatography.

Güteklasse

KO Validated

Immunogen

Recombinant protein encompassing a sequence within the C-terminus region of human GRK2. The exact sequence is proprietary.

Isotyp

IgG
anti-Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) (AA 440-689) antibody
ADRBK1 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated

anti-Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) antibody
ADRBK1 Reaktivität: Human, Maus, Ratte, Affe WB, ELISA, IHC, ICC Wirt: Maus Monoclonal 3F8 unconjugated

anti-Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) (AA 633-660), (C-Term) antibody
ADRBK1 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB0982 unconjugated

anti-Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) (Internal Region) antibody
ADRBK1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) (C-Term) antibody
ADRBK1 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated

anti-Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) (N-Term) antibody
ADRBK1 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated

anti-Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) (AA 2-221) antibody
ADRBK1 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated

anti-Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) (Ser129) antibody
ADRBK1 Reaktivität: Human, Maus, Ratte WB, ELISA Wirt: Kaninchen Polyclonal unconjugated

anti-Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) (C-Term) antibody
ADRBK1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated

anti-Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) (Internal Region) antibody
Verified ADRBK1 Reaktivität: Human WB, ELISA Wirt: Ziege Polyclonal unconjugated

Applikationshinweise

WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare

Positive Control: ADRBK1-transfected 293T
Validation: KO/KD, Overexpression

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

0.82 mg/mL

Buffer

1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

Konservierungsmittel

ProClin

Vorsichtsmaßnahmen

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Target

GRK2 (ADRBK1) (Adrenergic, Beta, Receptor Kinase 1 (ADRBK1))

Andere Bezeichnung

G protein-coupled receptor kinase 2 (ADRBK1 Produkte)

Synonyme

Adrbk-1 antikoerper, Bark-1 antikoerper, GRK2 antikoerper, betaARK1 antikoerper, BARK1 antikoerper, BETA-ARK1 antikoerper, GRK-2 antikoerper, Grk2 antikoerper, beta-adrenergic receptor kinase 1 antikoerper, G protein-coupled receptor kinase 2 antikoerper, Tsp_00497 antikoerper, grk2 antikoerper, Grk2 antikoerper, GRK2 antikoerper

Hintergrund

The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.

Molekulargewicht

80 kDa

Gen-ID

156

UniProt

P25098

Pathways

EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling