EIF4G2 Antikörper (C-Term)

Produktnummer ABIN2855138

Produktdetails anti-EIF4G2 Antikörper

Target: EIF4G2 (Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EIF4G2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus

Produktmerkmale: Rabbit Polyclonal antibody to DAP5 (eukaryotic translation initiation factor 4 gamma, 2)
DAP5 antibody [C2C3], C-term

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human DAP5. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: Mouse brain , HeLa , HepG2

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.39 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu EIF4G2

Target: EIF4G2 (Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2))

Andere Bezeichnung: eukaryotic translation initiation factor 4 gamma 2 (EIF4G2 Produkte)

Synonyme: AAG1 antikoerper, DAP5 antikoerper, NAT1 antikoerper, P97 antikoerper, NAT1B antikoerper, eif4g2 antikoerper, hm:zeh1307 antikoerper, wu:fa14h01 antikoerper, wu:fb44h01 antikoerper, wu:fb59c06 antikoerper, wu:fc21b05 antikoerper, EIF4G2 antikoerper, AA589388 antikoerper, DAP-5 antikoerper, E130105L11Rik antikoerper, Nat1 antikoerper, Natm1 antikoerper, p97 antikoerper, NAT1A antikoerper, im:7148615 antikoerper, wu:fb81f07 antikoerper, wu:fb82b06 antikoerper, wu:fb98h08 antikoerper, dap5 antikoerper, eif4g2.L antikoerper, nat1 antikoerper, eukaryotic translation initiation factor 4 gamma 2 antikoerper, eukaryotic translation initiation factor 4, gamma 2b antikoerper, eukaryotic translation initiation factor 4, gamma 2 antikoerper, eukaryotic translation initiation factor 4 gamma, 2 antikoerper, eIF4G-related protein NAT1 antikoerper, eukaryotic translation initiation factor 4, gamma 2a antikoerper, eukaryotic translation initiation factor 4 gamma, 2 S homeolog antikoerper, EIF4G2 antikoerper, eif4g2b antikoerper, Eif4g2 antikoerper, nat1 antikoerper, eif4g2a antikoerper, eif4g2.S antikoerper

Hintergrund: Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3, eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.

Molekulargewicht: 102 kDa

Gen-ID: 1982

UniProt: P78344