HGS Antikörper (C-Term)

Produktnummer ABIN2855140

Produktdetails anti-HGS Antikörper

Target: HGS (Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HGS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Rabbit Polyclonal antibody to HGS (hepatocyte growth factor-regulated tyrosine kinase substrate)
HGS antibody [C2C3], C-term

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human HGS. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Validation: Orthogonal

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu HGS

Target: HGS (Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS))

Andere Bezeichnung: hepatocyte growth factor-regulated tyrosine kinase substrate (HGS Produkte)

Synonyme: HRS antikoerper, Hrs antikoerper, fi34f05 antikoerper, zgc:63492 antikoerper, wu:fi34f05 antikoerper, Hgr antikoerper, ZFYVE8 antikoerper, CG2903 antikoerper, Dmel\\CG2903 antikoerper, HRS-2 antikoerper, Vps27 antikoerper, hrs antikoerper, l(2)23AB5 antikoerper, l(2)23Ad antikoerper, l(2)23Ad(Hrs) antikoerper, vps27 antikoerper, hgs antikoerper, hepatocyte growth factor-regulated tyrosine kinase substrate antikoerper, HGF-regulated tyrosine kinase substrate antikoerper, Hepatocyte growth factor regulated tyrosine kinase substrate antikoerper, hepatocyte growth factor-regulated tyrosine kinase substrate L homeolog antikoerper, HGS antikoerper, Hgs antikoerper, hgs antikoerper, Hrs antikoerper, hgs.L antikoerper

Hintergrund: The protein encoded by this gene regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome-dependent degradation.

Cellular Localization: Cytoplasm , Early endosome membrane, Peripheral membrane protein, Cytoplasmic side , Endosome , multivesicular body membrane, Peripheral membrane protein

Molekulargewicht: 86 kDa

Gen-ID: 9146

UniProt: O14964

Pathways: EGFR Signaling Pathway, CXCR4-mediated Signaling Events, Synaptic Vesicle Exocytosis, EGFR Downregulation