HBSAg Antikörper

Produktnummer ABIN285516

Produktdetails anti-HBSAg Antikörper

Target: HBSAg (HBsAg) (Hepatitis B Virus Surface Antigen (HBsAg))

Reaktivität: Hepatitis B Virus (HBV)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HBSAg Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Aufreinigung: purified

Reinheit: > 95 % pure

Immunogen: HBsAg antibody was raised in rabbit using subtypes ad and ay of human HBsAg as the immunogen.

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined byt he investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: Lot specific

Buffer: Protein A purified IgG fraction in 10 mM PBS, pH 7.2 with 0.1 % NaN3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Referenzen für anti-HBSAg Antikörper (ABIN285516)

Shi, Wu, Wang, Li, Yu, Wang, Yang, Li, Liang, Wen, Ying, Yuan: "Evaluation of antiviral - passive - active immunization ("sandwich") therapeutic strategy for functional cure of chronic hepatitis B in mice." in: EBioMedicine, Vol. 49, pp. 247-257, (2020) (PubMed).

Zahner, Glimm, Matono, Churin, Herebian, Mayatepek, Köhler, Gattenlöhner, Stinn, Tschuschner, Roderfeld, Roeb: "Hepatitis B virus surface proteins accelerate cholestatic injury and tumor progression in Abcb4-knockout mice." in: Oncotarget, Vol. 8, Issue 32, pp. 52560-52570, (2017) (PubMed).

Graumann, Churin, Tschuschner, Reifenberg, Glebe, Roderfeld, Roeb: "Genomic Methylation Inhibits Expression of Hepatitis B Virus Envelope Protein in Transgenic Mice: A Non-Infectious Mouse Model to Study Silencing of HBV Surface Antigen Genes." in: PLoS ONE, Vol. 10, Issue 12, pp. e0146099, (2016) (PubMed).

Zhang, Xia, Sun, Dai, Li, Schlaak, Lu: "In vitro and in vivo replication of a chemically synthesized consensus genome of hepatitis B virus genotype B." in: Journal of virological methods, Vol. 213, pp. 57-64, (2015) (PubMed).

Churin, Roderfeld, Stiefel, Würger, Schröder, Matono, Mollenkopf, Montalbano, Pompaiah, Reifenberg, Zahner, Ocker, Gerlich, Glebe, Roeb: "Pathological impact of hepatitis B virus surface proteins on the liver is associated with the host genetic background." in: PLoS ONE, Vol. 9, Issue 3, pp. e90608, (2014) (PubMed).

Cianciolo, Enghild, Pizzo: "Covalent complexes of antigen and alpha(2)-macroglobulin: evidence for dramatically-increased immunogenicity." in: Vaccine, Vol. 20, Issue 3-4, pp. 554-62, (2001) (PubMed).

Details zu HBSAg

Target: HBSAg (HBsAg) (Hepatitis B Virus Surface Antigen (HBsAg))

Andere Bezeichnung: HBsAg (HBsAg Produkte)

Substanzklasse: Viral Protein

Hintergrund: HBsAg is the surface antigen of the Hepatitis-B-Virus (HBV). It indicates current Hepatitis B infection.