HNRNPD/AUF1 Antikörper

Produktnummer ABIN2855184

Produktdetails anti-HNRNPD/AUF1 Antikörper

Target: HNRNPD/AUF1 (HNRNPD) (Heterogeneous Nuclear Ribonucleoprotein D (HNRNPD))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HNRNPD/AUF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Human, Maus

Produktmerkmale: Rabbit Polyclonal antibody to AUF1 (heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37 kDa))
AUF1 antibody

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human AUF1. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:5000-1:20000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: Mouse brain , 293T , Raji

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.45 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Referenzen für anti-HNRNPD/AUF1 Antikörper (ABIN2855184)

Hwang, Wagley, Law, Wei, Loh et al.: "Phosphorylation of poly(rC) binding protein 1 (PCBP1) contributes to stabilization of mu opioid receptor (MOR) mRNA via interaction with AU-rich element RNA-binding protein 1 (AUF1) and poly A ..." in: Gene, Vol. 598, pp. 113-130, (2017) (PubMed).

Details zu HNRNPD/AUF1

Target: HNRNPD/AUF1 (HNRNPD) (Heterogeneous Nuclear Ribonucleoprotein D (HNRNPD))

Andere Bezeichnung: heterogeneous nuclear ribonucleoprotein D (HNRNPD Produkte)

Synonyme: AUF1 antikoerper, AUF1A antikoerper, HNRPD antikoerper, P37 antikoerper, hnRNPD0 antikoerper, Auf1 antikoerper, Hnrnpd antikoerper, HNRNPD antikoerper, p37 antikoerper, auf1a antikoerper, hnrpd antikoerper, hnrnpd0 antikoerper, C230004L04 antikoerper, Hnrpd antikoerper, wu:fa28b06 antikoerper, zgc:162951 antikoerper, heterogeneous nuclear ribonucleoprotein D antikoerper, heterogeneous nuclear ribonucleoprotein D L homeolog antikoerper, HNRNPD antikoerper, Hnrnpd antikoerper, hnrnpd antikoerper, hnrnpd.L antikoerper

Hintergrund: This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It localizes to both the nucleus and the cytoplasm. This protein is implicated in the regulation of mRNA stability. Alternative splicing of this gene results in four transcript variants.

Cellular Localization: Nucleus

Molekulargewicht: 38 kDa

Gen-ID: 3184

UniProt: Q14103