HAX1 Antikörper
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- Target Alle HAX1 Antikörper anzeigen
- HAX1 (HCLS1 Associated Protein X-1 (HAX1))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser HAX1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
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Rabbit Polyclonal antibody to HAX1 (HCLS1 associated protein X-1)
HAX1 antibody - Aufreinigung
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human HAX1. The exact sequence is proprietary.
- Isotyp
- IgG
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- Applikationshinweise
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Kommentare
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Positive Control: Molt-4 , Raji
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 2.87 mg/mL
- Buffer
- 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- HAX1 (HCLS1 Associated Protein X-1 (HAX1))
- Andere Bezeichnung
- HCLS1 associated protein X-1 (HAX1 Produkte)
- Synonyme
- HAX1 antikoerper, hax1 antikoerper, HCLSBP1 antikoerper, HS1BP1 antikoerper, SCN3 antikoerper, HAX-1 antikoerper, Hs1bp1 antikoerper, HSP1BP-1 antikoerper, SIG-111 antikoerper, Silg111 antikoerper, mHAX-1s antikoerper, HCLS1 associated protein X-1 antikoerper, HCLS1 associated X-1 antikoerper, HAX1 antikoerper, hax1 antikoerper, Hax1 antikoerper
- Hintergrund
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The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene.
Cellular Localization: Mitochondrion , Endoplasmic reticulum , Nucleus membrane - Molekulargewicht
- 32 kDa
- Gen-ID
- 10456
- UniProt
- O00165
- Pathways
- Regulation of Actin Filament Polymerization
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