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MCL-1 Antikörper (Center)

MCL1 Reaktivität: Human WB, IF, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2855261
  • Target Alle MCL-1 (MCL1) Antikörper anzeigen
    MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))
    Bindungsspezifität
    • 27
    • 23
    • 16
    • 11
    • 9
    • 8
    • 8
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    Reaktivität
    • 149
    • 78
    • 66
    • 7
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 142
    • 12
    • 2
    • 1
    Kaninchen
    Klonalität
    • 138
    • 21
    Polyklonal
    Konjugat
    • 71
    • 12
    • 11
    • 10
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Dieser MCL-1 Antikörper ist unkonjugiert
    Applikation
    • 121
    • 66
    • 50
    • 46
    • 27
    • 26
    • 20
    • 20
    • 8
    • 8
    • 7
    • 5
    • 4
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    Produktmerkmale
    Rabbit Polyclonal antibody to MCL1 (myeloid cell leukemia sequence 1 (BCL2-related))
    MCL1 antibody
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human MCL1. The exact sequence is proprietary.
    Isotyp
    IgG
    Top Product
    Discover our top product MCL1 Primärantikörper
  • Applikationshinweise
    Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
    Kommentare

    Positive Control: Raji

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.89 mg/mL
    Buffer
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    Konservierungsmittel
    Thimerosal (Merthiolate)
    Vorsichtsmaßnahmen
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Takino, Sato, Nagamine, Hori: "The inhibition of Bax activation-induced apoptosis by RasGRP2 via R-Ras-PI3K-Akt signaling pathway in the endothelial cells." in: Scientific reports, Vol. 9, Issue 1, pp. 16717, (2019) (PubMed).

    Peng, Cheng, Hsu, Wu, Kuo, Liou, Chang, Jin, Shiah: "MPT0B098, a Microtubule Inhibitor, Suppresses JAK2/STAT3 Signaling Pathway through Modulation of SOCS3 Stability in Oral Squamous Cell Carcinoma." in: PLoS ONE, Vol. 11, Issue 7, pp. e0158440, (2017) (PubMed).

  • Target
    MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))
    Andere Bezeichnung
    MCL1 (MCL1 Produkte)
    Synonyme
    BCL2L3 antikoerper, EAT antikoerper, MCL1-ES antikoerper, MCL1L antikoerper, MCL1S antikoerper, Mcl-1 antikoerper, TM antikoerper, bcl2-L-3 antikoerper, mcl1/EAT antikoerper, AW556805 antikoerper, mcl-1 antikoerper, fb72f02 antikoerper, wu:fb70a08 antikoerper, wu:fb72f02 antikoerper, zfMLP1 antikoerper, zfMcl-1a antikoerper, zgc:109835 antikoerper, zgc:109763 antikoerper, E3 antikoerper, E3-2 antikoerper, RNE3 antikoerper, RNU107 antikoerper, SNORA63A antikoerper, elF-4AII antikoerper, MCL1, BCL2 family apoptosis regulator antikoerper, myeloid cell leukemia sequence 1 antikoerper, MCL1, BCL2 family apoptosis regulator a antikoerper, MCL1, BCL2 family apoptosis regulator b antikoerper, small nucleolar RNA, H/ACA box 63 antikoerper, MCL1 antikoerper, Mcl1 antikoerper, mcl1a antikoerper, mcl1b antikoerper, SNORA63 antikoerper
    Hintergrund
    The protein encoded by this gene belongs to the Bcl-2 family. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. The longer gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene product (isoform 2) promotes apoptosis and is death-inducing.

    Cellular Localization: Membrane, Single-pass membrane protein (Potential) , Cytoplasm , Mitochondrion , Nucleus , nucleoplasm
    Molekulargewicht
    37 kDa
    Gen-ID
    4170
    Pathways
    MAPK Signalweg
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