PPP2R1A Antikörper (Center)
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- Target Alle PPP2R1A Antikörper anzeigen
- PPP2R1A (Protein Phosphatase 2, Regulatory Subunit A, alpha (PPP2R1A))
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Bindungsspezifität
- Center
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PPP2R1A Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- Kreuzreaktivität
- Ratte (Rattus), Schwein, Rhesusaffen
- Kreuzreaktivität (Details)
- Rat (100 %), Pig (100 %), Rhesus Monkey (100 %)
- Produktmerkmale
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Rabbit Polyclonal antibody to PPP2R1A (serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform)
PPP2R1A antibody - Aufreinigung
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human PPP2R1A. The exact sequence is proprietary.
- Isotyp
- IgG
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- Applikationshinweise
- Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Immunoprecipitation Assay-dependent dilution Western blot 1:1000-1:10000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* ImmunoprecipitationAssay-dependent dilution Western blot1:1000-1:10000*
- Kommentare
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Positive Control: HeLa , NIH-3T3 , JC , BCL-1
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.96 mg/mL
- Buffer
- 1XPBS, 1 % BSA, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
- Konservierungsmittel
- Thimerosal (Merthiolate)
- Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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PP2A Deficiency Enhances Carcinogenesis of Lgr5+ Intestinal Stem Cells Both in Organoids and In Vivo." in: Cells, Vol. 9, Issue 1, (2020) (PubMed).
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PP2A Deficiency Enhances Carcinogenesis of Lgr5+ Intestinal Stem Cells Both in Organoids and In Vivo." in: Cells, Vol. 9, Issue 1, (2020) (PubMed).
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- Target
- PPP2R1A (Protein Phosphatase 2, Regulatory Subunit A, alpha (PPP2R1A))
- Andere Bezeichnung
- PPP2R1A (PPP2R1A Produkte)
- Synonyme
- PP2A-Aalpha antikoerper, PP2AAALPHA antikoerper, PR65A antikoerper, PR65 antikoerper, pp2a-aalpha antikoerper, pp2aaalpha antikoerper, ppp2r1a antikoerper, pr65a antikoerper, wu:fa02h04 antikoerper, zgc:56296 antikoerper, 6330556D22Rik antikoerper, PP2A antikoerper, ppp2r1a-a antikoerper, ppp2r1a-b antikoerper, protein phosphatase 2 scaffold subunit Aalpha antikoerper, protein phosphatase 2 scaffold subunit A alpha antikoerper, protein phosphatase 2 regulatory subunit A, alpha L homeolog antikoerper, protein phosphatase 2 regulatory subunit A, alpha antikoerper, protein phosphatase 2, regulatory subunit A, beta a antikoerper, serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform antikoerper, protein phosphatase 2, regulatory subunit A, alpha isoform antikoerper, protein phosphatase 2, regulatory subunit A, alpha antikoerper, protein phosphatase 2 regulatory subunit A, alpha S homeolog antikoerper, PPP2R1A antikoerper, Ppp2r1a antikoerper, ppp2r1a.L antikoerper, ppp2r1a antikoerper, ppp2r1ba antikoerper, LOC583227 antikoerper, ppp2r1a.S antikoerper
- Hintergrund
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This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes an alpha isoform of the constant regulatory subunit A.
- Molekulargewicht
- 65 kDa
- Gen-ID
- 5518
- Pathways
- PI3K-Akt Signalweg, Mitotic G1-G1/S Phases, M Phase, Hepatitis C, Toll-Like Receptors Cascades
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