PSMD2 Antikörper

Produktnummer ABIN2855347

Produktdetails anti-PSMD2 Antikörper

Target: PSMD2 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 2 (PSMD2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMD2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Kreuzreaktivität: Human, Maus

Produktmerkmale: Rabbit Polyclonal antibody to PSMD2 (26S proteasome non-ATPase regulatory subunit 2)
PSMD2 antibody

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human PSMD2. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: JC , BCL-1 , A431

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.82 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu PSMD2

Target: PSMD2 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 2 (PSMD2))

Andere Bezeichnung: proteasome 26S subunit, non-ATPase 2 (PSMD2 Produkte)

Synonyme: DDBDRAFT_0192101 antikoerper, DDBDRAFT_0232978 antikoerper, DDB_0192101 antikoerper, DDB_0232978 antikoerper, zgc:65921 antikoerper, MGC83233 antikoerper, psmd2 antikoerper, MGC97650 antikoerper, PSMD2 antikoerper, P97 antikoerper, RPN1 antikoerper, S2 antikoerper, TRAP2 antikoerper, 9430095H01Rik antikoerper, AA407121 antikoerper, TEG-190 antikoerper, Tex190 antikoerper, 26S proteasome non-ATPase regulatory subunit 2 antikoerper, 26S proteasome regulatory subunit S2 antikoerper, proteasome 26S subunit, non-ATPase 2 antikoerper, proteasome 26S subunit, non-ATPase 2 L homeolog antikoerper, proteasome 26S subunit, non-ATPase 2 S homeolog antikoerper, proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 antikoerper, psmD2 antikoerper, NAEGRDRAFT_83014 antikoerper, DICPUDRAFT_55026 antikoerper, psmd2 antikoerper, psmd2.L antikoerper, psmd2.S antikoerper, PSMD2 antikoerper, Psmd2 antikoerper

Hintergrund: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. In addition to participation in proteasome function, this subunit may also participate in the TNF signalling pathway since it interacts with the tumor necrosis factor type 1 receptor. A pseudogene has been identified on chromosome 1.

Molekulargewicht: 100 kDa

Gen-ID: 5708

UniProt: Q13200

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway