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EEF1A2 Antikörper

KO Validated EEF1A2 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2855358
  • Target Alle EEF1A2 Antikörper anzeigen
    EEF1A2 (Eukaryotic Translation Elongation Factor 1 alpha 2 (EEF1A2))
    Reaktivität
    • 36
    • 28
    • 13
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 46
    • 1
    • 1
    Kaninchen
    Klonalität
    • 48
    Polyklonal
    Konjugat
    • 17
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser EEF1A2 Antikörper ist unkonjugiert
    Applikation
    • 41
    • 21
    • 17
    • 13
    • 13
    • 9
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Spezifität
    Based on a BLAST result, it may also cross with human EEF1A1.
    Kreuzreaktivität
    Human, Maus, Ratte, Zebrafisch (Danio rerio)
    Produktmerkmale
    Rabbit Polyclonal antibody to EEF1A2 (eukaryotic translation elongation factor 1 alpha 2)
    EEF1A2 antibody
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Güteklasse
    KO Validated
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human EEF1A2. The exact sequence is proprietary.
    Isotyp
    IgG
  • Applikationshinweise
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Kommentare

    Positive Control: Mouse brain , mouse muscle , rat brain , 293T

    Validation: KO/KD

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.21 mg/mL
    Buffer
    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Losada, Muñoz-Alonso, García, Sánchez-Murcia, Martínez-Leal, Domínguez, Lillo, Gago, Galmarini: "Translation Elongation Factor eEF1A2 is a Novel Anticancer Target for the Marine Natural Product Plitidepsin." in: Scientific reports, Vol. 6, pp. 35100, (2018) (PubMed).

  • Target
    EEF1A2 (Eukaryotic Translation Elongation Factor 1 alpha 2 (EEF1A2))
    Andere Bezeichnung
    eukaryotic translation elongation factor 1 alpha 2 (EEF1A2 Produkte)
    Synonyme
    EEF1AL antikoerper, EF-1-alpha-2 antikoerper, EF1A antikoerper, HS1 antikoerper, STN antikoerper, STNL antikoerper, EEF1A2 antikoerper, Eef1a antikoerper, S1 antikoerper, wasted antikoerper, wst antikoerper, Ps10 antikoerper, RATPS10 antikoerper, Stnl antikoerper, eef1al antikoerper, ef1a antikoerper, stnl antikoerper, EEF1A-2 antikoerper, zgc:92085 antikoerper, eukaryotic translation elongation factor 1 alpha 2 antikoerper, eukaryotic translation elongation factor 1 alpha 1 antikoerper, eukaryotic translation elongation factor 1 alpha 2 S homeolog antikoerper, putative elongation factor 1-alpha-like 3 antikoerper, EEF1A2 antikoerper, EEF1A1 antikoerper, Eef1a2 antikoerper, eef1a2.S antikoerper, eef1a2 antikoerper, LOC739210 antikoerper, EEF1 antikoerper, eef1 antikoerper
    Hintergrund
    This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 2) is expressed in brain, heart and skeletal muscle, and the other isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas. This gene may be critical in the development of ovarian cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    Cellular Localization: Nucleus
    Molekulargewicht
    50 kDa
    Gen-ID
    1917
    UniProt
    Q05639
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