BAG2 Antikörper

Produktnummer ABIN2855386

Produktdetails anti-BAG2 Antikörper

Target: BAG2 (BCL2-Associated Athanogene 2 (BAG2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BAG2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human

Produktmerkmale: Rabbit Polyclonal antibody to BAG2 (BAG family molecular chaperone regulator 2)
BAG2 antibody

Aufreinigung: Purified by antigen-affinity chromatography.

Güteklasse: KO Validated

Immunogen: Recombinant protein encompassing a sequence within the center region of human BAG2. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: A431 , HeLa

Validation: KO/KD

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu BAG2

Target: BAG2 (BCL2-Associated Athanogene 2 (BAG2))

Andere Bezeichnung: BCL2 associated athanogene 2 (BAG2 Produkte)

Synonyme: bag2 antikoerper, MGC89300 antikoerper, BAG2 antikoerper, ATBAG2 antikoerper, BCL-2-associated athanogene 2 antikoerper, MTG10.13 antikoerper, MTG10_13 antikoerper, BAG-2 antikoerper, dJ417I1.2 antikoerper, zgc:64195 antikoerper, 2610042A13Rik antikoerper, BC016230 antikoerper, BCL2 associated athanogene 2 antikoerper, BCL-2-associated athanogene 2 antikoerper, BCL2-associated athanogene 2 antikoerper, Bcl2-associated athanogene 2 antikoerper, bag2 antikoerper, BAG2 antikoerper, Bag2 antikoerper

Hintergrund: BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.

Molekulargewicht: 24 kDa

Gen-ID: 9532

UniProt: O95816