Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

PYCARD Antikörper

PYCARD Reaktivität: Human WB, IF, IHC (p), ICC, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2855403
  • Target Alle PYCARD Antikörper anzeigen
    PYCARD (PYD and CARD Domain Containing (PYCARD))
    Reaktivität
    • 56
    • 10
    • 9
    • 1
    • 1
    • 1
    Human
    Wirt
    • 47
    • 7
    • 3
    Kaninchen
    Klonalität
    • 46
    • 11
    Polyklonal
    Konjugat
    • 32
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser PYCARD Antikörper ist unkonjugiert
    Applikation
    • 39
    • 23
    • 15
    • 12
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Human
    Produktmerkmale
    Rabbit Polyclonal antibody to TMS1 (PYD and CARD domain containing)
    TMS1 antibody [N1C3]
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human TMS1. The exact sequence is proprietary.
    Isotyp
    IgG
    Top Product
    Discover our top product PYCARD Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Kommentare

    Positive Control: THP-1 , DDDDK-tagged PYCARD-transfected 293T

    Validation: Overexpression

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
    Konservierungsmittel
    Thimerosal (Merthiolate)
    Vorsichtsmaßnahmen
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    PYCARD (PYD and CARD Domain Containing (PYCARD))
    Andere Bezeichnung
    PYD and CARD domain containing (PYCARD Produkte)
    Synonyme
    ASC antikoerper, CARD5 antikoerper, TMS antikoerper, TMS-1 antikoerper, TMS1 antikoerper, 9130417A21Rik antikoerper, Asc antikoerper, TNS1 antikoerper, masc antikoerper, asc1 antikoerper, zAsc antikoerper, zgc:109874 antikoerper, PYD and CARD domain containing antikoerper, PYCARD antikoerper, Pycard antikoerper, pycard antikoerper
    Hintergrund
    This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm, however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene.

    Cellular Localization: Cytoplasm
    Molekulargewicht
    22 kDa
    Gen-ID
    29108
    UniProt
    Q9ULZ3
    Pathways
    Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation, Inflammasome
Sie sind hier:
Kundenservice