Desmoglein 2 Antikörper (N-Term)
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- Target Alle Desmoglein 2 (DSG2) Antikörper anzeigen
- Desmoglein 2 (DSG2)
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Bindungsspezifität
- N-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Desmoglein 2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- Kreuzreaktivität
- Human, Maus
- Produktmerkmale
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Rabbit Polyclonal antibody to Desmoglein 2 (desmoglein-2)
Desmoglein 2 antibody [N1N2], N-term - Aufreinigung
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the N-terminus region of human Desmoglein 2. The exact sequence is proprietary.
- Isotyp
- IgG
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- Applikationshinweise
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Kommentare
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Validation: Orthogonal
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.36 mg/mL
- Buffer
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- Desmoglein 2 (DSG2)
- Andere Bezeichnung
- desmoglein 2 (DSG2 Produkte)
- Synonyme
- DSG2 antikoerper, dsc antikoerper, dsga antikoerper, si:dkeyp-51f12.6 antikoerper, wu:fj23f02 antikoerper, ARVC10 antikoerper, ARVD10 antikoerper, CDHF5 antikoerper, CMD1BB antikoerper, HDGC antikoerper, AA408168 antikoerper, D18Ertd293e antikoerper, desmoglein 2 antikoerper, desmoglein 2, tandem duplicate 1 antikoerper, DSG2 antikoerper, dsg2.1 antikoerper, dsg2 antikoerper, Dsg2 antikoerper
- Hintergrund
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Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. This gene product is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10.
Cellular Localization: Cell membrane , Cell junction , desmosome - Molekulargewicht
- 122 kDa
- Gen-ID
- 1829
- UniProt
- Q14126
- Pathways
- Cell-Cell Junction Organization
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