MUSK Antikörper (N-Term)
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- Target Alle MUSK Antikörper anzeigen
- MUSK (Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MUSK Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Kreuzreaktivität
- Maus, Ratte (Rattus), Rind (Kuh)
- Kreuzreaktivität (Details)
- Mouse (97 %), Rat (98 %), Bovine (97 %)
- Produktmerkmale
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Rabbit Polyclonal antibody to MUSK (muscle, skeletal, receptor tyrosine kinase)
MUSK antibody [N1N2], N-term - Aufreinigung
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the N-terminus region of human MUSK. The exact sequence is proprietary.
- Isotyp
- IgG
- Top Product
- Discover our top product MUSK Primärantikörper
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- Applikationshinweise
- Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
- Kommentare
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Positive Control: NT2D1
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
- Konservierungsmittel
- Thimerosal (Merthiolate)
- Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- MUSK (Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK))
- Andere Bezeichnung
- MUSK (MUSK Produkte)
- Synonyme
- unp antikoerper, fj98e12 antikoerper, zgc:63467 antikoerper, wu:fj98e12 antikoerper, si:dz46m7.2 antikoerper, si:dz57f23.3 antikoerper, si:busm1-57f23.3 antikoerper, musk-A antikoerper, MuSK antikoerper, MUSK antikoerper, Mdk4 antikoerper, Mlk antikoerper, Nsk1 antikoerper, Nsk2 antikoerper, Nsk3 antikoerper, muscle antikoerper, muscle associated receptor tyrosine kinase antikoerper, muscle, skeletal, receptor tyrosine kinase antikoerper, muscle associated receptor tyrosine kinase S homeolog antikoerper, MUSK antikoerper, musk antikoerper, musk.S antikoerper, Musk antikoerper
- Hintergrund
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Intercellular communication is often mediated by receptors on the surface of one cell that recognize and are activated by specific protein ligands released by other cells. Members of one class of cell surface receptors, receptor tyrosine kinases (RTKs), are characterized by having a cytoplasmic domain containing intrinsic tyrosine kinase activity. This kinase activity is regulated by the binding of a cognate ligand to the extracellular portion of the receptor. DeChiara et al. (1996) [PubMed 8653786] noted that the RTKs, known to be expressed in cell type-specific fashions, play a role critical for the growth and differentiation of those cell types. For example, members of the neural-specific TRK family that recognize nerve growth factor are absolutely required for the survival and development of discrete neuronal subpopulations, and the receptor tyrosine kinases TIE1 (MIM 600222) and TIE2 (MIM 600221) play a critical role in the development of normal blood vessels.[supplied by OMIM]
Cellular Localization: Membrane, Single-pass type I membrane protein - Molekulargewicht
- 97 kDa
- Gen-ID
- 4593
- Pathways
- RTK Signalweg, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of Cell Size, Skeletal Muscle Fiber Development
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