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TP53BP1 Antikörper (N-Term)

Name: TP53BP1 Antikörper (N-Term)
Brand: antibodies-online
SKU: ABIN2855433
Price: 630.63 EUR
Availability: InStock

KO Validated TP53BP1 Reaktivität: Human WB, IF, ICC, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

IHC-P Image 53BP1 antibody [N1], N-term detects 53BP1 protein at nucleus on human colon carcinoma by immunohistochemical analysis. (TP53BP1 Antikörper (N-Term))

IHC

WB Image 53BP1 antibody [N1], N-term detects TP53BP1 protein by Western blot analysis. (TP53BP1 Antikörper (N-Term))

ICC/IF Image 53BP1 antibody [N1], N-term detects 53BP1 protein at nucleus by immunofluorescent analysis. (TP53BP1 Antikörper (N-Term))

WB Image Various whole cell extracts (30 μg) were separated by 5% SDS-PAGE, and the membrane was blotted with 53BP1 antibody [N1], N-term , diluted at 1:500. (TP53BP1 Antikörper (N-Term))

4 Abbildungen

Produktnummer ABIN2855433

Datenblatt (PDF)

Target Alle TP53BP1 Antikörper anzeigen

TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))
Bindungsspezifität
32

21

15

11

8

6

4

4

3

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
N-Term
Reaktivität
104

63

61

7

4

4

4

3

2

2

1

1

1
Human
Wirt
107

9

2

1
Kaninchen
Passende Sekundärantikörper
Klonalität
101

18
Polyklonal
Konjugat
58

5

5

5

5

5

5

5

2

2

2

2

2

2

2

2

2

2

2

2

2
Dieser TP53BP1 Antikörper ist unkonjugiert
Applikation
44

30

27

27

26

17

16

11

10

6

6

4

4

2

2

1

1
Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität

Human, Maus

Produktmerkmale

Rabbit Polyclonal antibody to 53BP1 (tumor protein p53 binding protein 1)
53BP1 antibody [N1], N-term

Aufreinigung

Purified by antigen-affinity chromatography.

Güteklasse

KO Validated

Immunogen

Recombinant protein encompassing a sequence within the N-terminus region of human 53BP1. The exact sequence is proprietary.

Isotyp

IgG

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TP53BP1 Reaktivität: Human, Maus, Ratte WB, ICC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

anti-Tumor Protein P53 Binding Protein 1 (TP53BP1) (pSer25), (pSer29) antibody
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anti-Tumor Protein P53 Binding Protein 1 (TP53BP1) (N-Term) antibody
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anti-Tumor Protein P53 Binding Protein 1 (TP53BP1) (AA 1763-1977) antibody
TP53BP1 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated

anti-Tumor Protein P53 Binding Protein 1 (TP53BP1) (pThr543) antibody
TP53BP1 Reaktivität: Human, Affe WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Tumor Protein P53 Binding Protein 1 (TP53BP1) (AA 149-259) antibody
TP53BP1 Reaktivität: Human WB, BI Wirt: Maus Monoclonal 19-53BP1 unconjugated

anti-Tumor Protein P53 Binding Protein 1 (TP53BP1) (N-Term) antibody
TP53BP1 Reaktivität: Human, Maus, Ratte WB, IHC, IF, IC Wirt: Kaninchen Polyclonal unconjugated

anti-Tumor Protein P53 Binding Protein 1 (TP53BP1) (AA 1724-1964) antibody
TP53BP1 Reaktivität: Human WB, IHC, ICC, IP Wirt: Kaninchen Polyclonal unconjugated

anti-Tumor Protein P53 Binding Protein 1 (TP53BP1) (AA 1758-1972) antibody
TP53BP1 Reaktivität: Human IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare

Positive Control: 293T , HeLa , Neuro 2A , C8D30 , NIH-3T3
Validation: KO/KD

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 mg/mL

Buffer

0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel

Thimerosal (Merthiolate)

Vorsichtsmaßnahmen

This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Target

TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))

Andere Bezeichnung

tumor protein p53 binding protein 1 (TP53BP1 Produkte)

Synonyme

TP53BP1 antikoerper, MGC160112 antikoerper, 53BP1 antikoerper, Tp53bp1 antikoerper, m53BP1 antikoerper, p202 antikoerper, Trp53bp1 antikoerper, tumor protein p53 binding protein 1 antikoerper, tumor suppressor p53-binding protein 1 antikoerper, tumor protein p53 binding protein 1 (predicted), 5 prime antikoerper, transformation related protein 53 binding protein 1 antikoerper, TP53BP1 antikoerper, tp53bp1 antikoerper, LOC100550605 antikoerper, Trp53bp1 antikoerper, Tp53bp1 antikoerper

Hintergrund

May have a role in checkpoint signaling during mitosis (By similarity). Enhances TP53-mediated transcriptional activation. Plays a role in the response to DNA damage.

Cellular Localization: Nucleus , Kinetochore

Molekulargewicht

214 kDa

Gen-ID

7158

UniProt

Q12888

Pathways

DNA Reparatur