ABCB11 Antikörper (Internal Region)
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- Target Alle ABCB11 Antikörper anzeigen
- ABCB11 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ABCB11 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Produktmerkmale
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Rabbit Polyclonal antibody to BSEP (ATP-binding cassette, sub-family B (MDR/TAP), member 11)
BSEP antibody [N3C1], Internal - Aufreinigung
- Affinity purified by Protein A.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human BSEP. The exact sequence is proprietary.
- Isotyp
- IgG
- Top Product
- Discover our top product ABCB11 Primärantikörper
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- Applikationshinweise
- Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
- Kommentare
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Positive Control: Jurkat
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 9.01 mg/mL
- Buffer
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
- Konservierungsmittel
- Thimerosal (Merthiolate)
- Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- ABCB11 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11))
- Andere Bezeichnung
- BSEP (ABCB11 Produkte)
- Synonyme
- ABCB11 antikoerper, Bsep antikoerper, ABC16 antikoerper, BRIC2 antikoerper, BSEP antikoerper, PFIC-2 antikoerper, PFIC2 antikoerper, PGY4 antikoerper, SPGP antikoerper, Lith1 antikoerper, BSEP/SPGP antikoerper, Spgp antikoerper, ATP binding cassette subfamily B member 11 antikoerper, bile salt export pump antikoerper, ATP-binding cassette, sub-family B (MDR/TAP), member 11 antikoerper, ABCB11 antikoerper, LOC100489744 antikoerper, LOC100565276 antikoerper, EDI_111220 antikoerper, EDI_272930 antikoerper, abcb11 antikoerper, Abcb11 antikoerper
- Hintergrund
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The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy.
Cellular Localization: Membrane - Molekulargewicht
- 146 kDa
- Gen-ID
- 8647
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